National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Effects of hyaluronan on properties of eye drops
Chromá, Kateřina ; Mravec, Filip (referee) ; Pekař, Miloslav (advisor)
Modifying eye drops using hyaluronan leads to an increased retention time on the eye surface. Long-lasting observations of the stability of two different eye drops, Opthalmo-Septonex and Visine Classic, after the addition of hyaluronan with varying concentration are presented in this work. The interactions of hyaluronan with the eye drops, or their components benzalkonium chloride and tetryzoline, are investigated by monitoring particle sizes and the charge of the molecules. Additionally, rheological examinations of the samples are done and the mucoadhesion index is determined by using the mucine method.
Effects of hyaluronan on properties of eye drops
Chromá, Kateřina ; Mravec, Filip (referee) ; Pekař, Miloslav (advisor)
Modifying eye drops using hyaluronan leads to an increased retention time on the eye surface. Long-lasting observations of the stability of two different eye drops, Opthalmo-Septonex and Visine Classic, after the addition of hyaluronan with varying concentration are presented in this work. The interactions of hyaluronan with the eye drops, or their components benzalkonium chloride and tetryzoline, are investigated by monitoring particle sizes and the charge of the molecules. Additionally, rheological examinations of the samples are done and the mucoadhesion index is determined by using the mucine method.

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