National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Refinement of tissue diagnostics in the transplant program
Balko, Jan ; Zámečník, Josef (advisor) ; Škarda, Jozef (referee) ; Němejcová, Kristýna (referee)
Refinement of tissue diagnostics in the transplant program Abstract The thesis describes tissue diagnostics of organ transplants of the donor as well as recipient. In case of donated organs (grafts), it aims to improve the provisional scoring system of graft rejection after uterine transplantation. Using histopathological methods including immunohistochemistry, it compares lymphocytic population classified in the scoring system with histopathological findings within the resected uteri of women who underwent hysterectomy for benign reasons. The aim was to validate the necessity of the category of so called borderline changes, whose morphology was proven to overlap with physiological finding within healthy uterine cervix. Therefore, there is no need for immunosuppressive therapy in such cases. In case of recipients, the thesis investigates the role of pulmonary megakaryocytes in explanted lungs after transplantation. The idea was to elucidate pathogenesis of the diseases leading to the need of transplantation itself. Pulmonary megakaryocytes within explanted lungs of various recipients were mapped using histopathological methods and immunohistochemistry. The strikingly increased number of such cells was detected among vascular disorders, especially idiopathic pulmonary hypertension. This finding could...
Uterus transplantation as a path to motherhood
Hlaváčová, Žaneta ; Sokolová, Věra (advisor) ; Hasmanová Marhánková, Jaroslava (referee)
This thesis describes relatively new method of assisted reproduction. Uterus transplantation is viewed from feminist perspective, and its potential benefits and risks in wider ethical and social contexts on theoretical level are being considered. It reveals how womanhood and motherhood are constructed in different discourses in context of uterine transplantation through critical reading and thinking. By using of critical discourse analysis I focus on texts produced on this subject in the popular and professional discourse and reveal what kind of gender stereotypes and constructs they are using to support their arguments. These areas of our everyday lives have great power in society and influence the way we perceive and construct reality and thus participate in its creation. Key words: Uterus transplantation, infertility, motherhood, reproductive technology, gender roles

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