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Determination of hydraulic characteristics of soil in a selected area
Salač, Jan ; Doležal, Petr (referee) ; Kameníčková, Ivana (advisor)
The diploma thesis is focused on issues of measurement and evaluation of hydraulic characteristics of soil. In the literary research, the definitions of hydraulic conductivity and retention curve of soil moisture, their measurements in laboratory and field conditions and the prediction of these characteristics by using of pedotransfer functions. In the practical part of the diploma thesis, an evaluation of the hydraulic conductivity of soil from the experimental areas near the village Bohaté Málkovice. Two-cylindrical and mini-disc infiltration meters were used for field measurements, and a constant-gradient permeameter was used in the laboratory. Physical and empirical equations were used to evaluate the hydraulic conductivity. The results were processed numerically, tabulated and then compared.
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Bioinformatics Tool for Protein Structure Prediction
Plaga, Michal ; Burgetová, Ivana (referee) ; Martínek, Tomáš (advisor)
The goal of this thesis is test and comparation of the offline tools for prediction of protein structure and creation of metaprediktor, which allows the user to select the appropriate tool, according to given parameters. Testing tool is based on a dataset of proteins, which is based on the SCOP database and it is trying to be as balanced as possible to include proteins from different families and thus could best evaluate individual tools. The results of this thesis are requirements of metaprediktor and also which data and settings can be allowed and processed and how it will be implemented.
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Determination of hydraulic characteristics of soil in a selected area
Salač, Jan ; Doležal, Petr (referee) ; Kameníčková, Ivana (advisor)
The diploma thesis is focused on issues of measurement and evaluation of hydraulic characteristics of soil. In the literary research, the definitions of hydraulic conductivity and retention curve of soil moisture, their measurements in laboratory and field conditions and the prediction of these characteristics by using of pedotransfer functions. In the practical part of the diploma thesis, an evaluation of the hydraulic conductivity of soil from the experimental areas near the village Bohaté Málkovice. Two-cylindrical and mini-disc infiltration meters were used for field measurements, and a constant-gradient permeameter was used in the laboratory. Physical and empirical equations were used to evaluate the hydraulic conductivity. The results were processed numerically, tabulated and then compared.
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Ab initio prediction of the membrane protein structures
Sokol, Albert ; Fišer, Radovan (advisor) ; Plocek, Vítězslav (referee)
Knowledge of the three dimensional structure of the protein is extremely important for a full understanding of its function and molecular proteins interaction. The structure is typically determined experimentally by X-ray crystallography and NMR spectroscopy, unfortunately membrane proteins provide numerous problems for these methods. A possible solution is the computational prediction. Ab initio prediction of three-dimensional models of the membrane proteins is a complex process which cannot use any available protein structure as a general template. There are few softwares that deal with this process and selected four are described in detail in this work. These are two programs for the prediction of transmembrane helical proteins (Rosetta, EVfold_membrane) and two for the prediction of transmembrane beta barrels (EVfold_bb, 3D-SPOT). The main approaches that are used in the prediction of the three-dimensional structure of a protein are inserting short segments of amino acid sequences which are derived from the determined protein structures (Rosetta), using evolutionary information from many other protein sequences (EVfold) and formation of the beta barrel domains based on combining adjacent antiparallel beta chains (3D-SPOT). Every software uses a variety of external programs to address specific...
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Bioinformatics Tool for Protein Structure Prediction
Plaga, Michal ; Burgetová, Ivana (referee) ; Martínek, Tomáš (advisor)
The goal of this thesis is test and comparation of the offline tools for prediction of protein structure and creation of metaprediktor, which allows the user to select the appropriate tool, according to given parameters. Testing tool is based on a dataset of proteins, which is based on the SCOP database and it is trying to be as balanced as possible to include proteins from different families and thus could best evaluate individual tools. The results of this thesis are requirements of metaprediktor and also which data and settings can be allowed and processed and how it will be implemented.
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