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National Repository of Grey Literature

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Antimicrobial peptides isolated from the venom of wild bee Panurgus calcaratus Čujová, Sabína ; Monincová, Lenka ; Slaninová, Jiřina ; Bednárová, Lucie ; Čeřovský, Václav Three novel peptides designated as PNG-1, PNG-K and PNG-R were isolated from the venom of the solitary bee Panurgus calcaratus. They exhibited antimicrobial activity against Grampositive and -negative bacteria and fungi. In this work we focused on the characterization of PNG-R which is unique 25 amino acid residues and two disulfide bridges containing peptide. The secondary structure of PNG-R was studied by circular dichroism spectroscopy measured in water and in the presence of trifluoroethanol or sodium dodecyl sulfate. Detailed record

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