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Correlation between inspiratory muscle strength and fitness in patients before lung transplantation
Stehnová, Tereza ; Babková, Lenka (advisor) ; Wanke, Ondřej (referee)
Introduction: Exercise capacity is frequently limited in lung transplantation candidates which can result in worse clinical outcomes of the transplantation itself. There can be several factors limiting exercise capacity, the purpose of this thesis is to determine the influence of inspiratory muscle strenght on reduced exercise capacity in these patients. The aim of this study is also to evaluate whether the Timed Up and Go Test is feasible for exercise capacity assessment in lung transplantation candidates as an alternative for the Six- Minute Walking Test. Methods: 14 patients with end-stage chronic lung disease considered for the lung transplantation waiting list inclusion performed Six-Minute Walking Test, Timed Up and Go Test and inspiratory muscle strenght evaluation using POWERbreathe® K5 (S-Index value). Correlations of the results of these tests were investigated. They were also evaluated separately for a group of patients with inspiratory muscle weakness (S-Index values lower than 80 % of predicted values). Results: No statistically significant correlation was found between exercise capacity tests and inspiratory muscle strenght. The correlation between the results of Six-Minute Walking Test and S-Index values was higher in patients with inspiratory muscle weakness. Statistically...

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