|
|
CISCO security laboratory exercise
Švec, Martin ; Hajný, Jan (referee) ; Pelka, Tomáš (advisor)
The main purpose of this diploma thesis is to become familiar with the principles and technical solutions regarding security components of Cisco company and configure assigned system according to valid rules of security. In introduction are explained the reasons for networks security solutions. This work also analyses different kinds of security weaknesses which include deficiencies of networks protocols and also the attacks from hackers. The principle of firewall is described and also its particular types. This work is focused on explanation and classification of PIX firewall, which has dominant role in the field of network security. The other equipments of Cisco, which are improving the level of security, are also mentioned. The practical part of this diploma thesis is composed of networks connections and configuration of system consisting of router, PIX firewall and switch. It also includes the detailed procedure and description of configuration of network equipments. The focus is put on minimalization of threats and elimination of DoS attacks.
|
|
|
New regulatory mechanisms of microtubule nucleation
Černohorská, Markéta ; Dráber, Pavel (advisor) ; Binarová, Pavla (referee) ; Hašek, Jiří (referee)
MT nucleation from γ-tubulin complexes, located at centrosome, is an essential step in the formation of MT cytoskeleton. In mammalian cells, -tubulin is encoded by two genes. We functionally characterized two γ-tubulin proteins and have found that both are functionally equivalent. γ-Tubulin 2 is able to substitute for γ-tubulin 1 in MT nucleation. However, we revealed that unlike TUBG1, TUBG2 expression is downregulated in mouse preimplantation development. Mast cells represent effectors of the allergy reaction. Their activation by antigen induces number of cellular processes such as degranulation, proliferation and cytoskeleton rearrangements. The regulatory mechanisms of MT reorganization during mast cell activation are unknown. We identified new signaling proteins, GIT1 and PIX that interact with - tubulin. Depletion of GIT1 or PIX leads to changes in MT nucleation. GIT1 is phosphorylated on tyrosine and associates with γ-tubulin in a Ca2+ -dependent manner. Our data suggested a novel signaling pathway for MT rearrangement in mast cells where tyrosine kinase-activated GIT1 and βPIX work in concert with Ca2+ signaling to regulate MT nucleation. We tested the capability of GIT1 and PIX to influence -tubulin function in more cell types. We found out that GIT1/βPIX signaling proteins together...
|
|
|
CISCO security laboratory exercise
Švec, Martin ; Hajný, Jan (referee) ; Pelka, Tomáš (advisor)
The main purpose of this diploma thesis is to become familiar with the principles and technical solutions regarding security components of Cisco company and configure assigned system according to valid rules of security. In introduction are explained the reasons for networks security solutions. This work also analyses different kinds of security weaknesses which include deficiencies of networks protocols and also the attacks from hackers. The principle of firewall is described and also its particular types. This work is focused on explanation and classification of PIX firewall, which has dominant role in the field of network security. The other equipments of Cisco, which are improving the level of security, are also mentioned. The practical part of this diploma thesis is composed of networks connections and configuration of system consisting of router, PIX firewall and switch. It also includes the detailed procedure and description of configuration of network equipments. The focus is put on minimalization of threats and elimination of DoS attacks.
|
guest ::
