|
|
Solubilization in catanionic surfactant systems
Konečná, Anna ; Krouská, Jitka (referee) ; Mravec, Filip (advisor)
This bachelor thesis deals with the solubilization of hydrophobic dyes in systems of positively charged catanionic vesicles. The aim of the work was to determine their solubilization capacity. Vesicular systems were prepared from oppositely charged surfactants CTAB and SDS. To increase the stability of the vesicles, cholesterol and the positively charged double-chain surfactant DODAC were added to their structure. DODAC also gave the system a positive charge. To determine the solubilization capacity, the dyes 1-Naphthol, Sudan Red G and Oil Red O were used. For sample preparation two methods were used, spontaneous and direct solubilization. The measurement was performed after 1, 2, 3 and 7 days from the preparation of the samples by UV-VIS spectrophotometry. The solubilization capacity was determined from the measured absorbance by calculation from the calibration curves. The results indicate that direct solubilization is slightly more effective than spontaneous solubilization. Of the selected dyes, 1-Naphthol is the substance with the smallest molecule, and therefore it seems to be 100% solubilized in the vesicle system.
|
|
|
Solubilization in catanionic surfactant systems
Konečná, Anna ; Krouská, Jitka (referee) ; Mravec, Filip (advisor)
This bachelor thesis deals with the solubilization of hydrophobic dyes in systems of positively charged catanionic vesicles. The aim of the work was to determine their solubilization capacity. Vesicular systems were prepared from oppositely charged surfactants CTAB and SDS. To increase the stability of the vesicles, cholesterol and the positively charged double-chain surfactant DODAC were added to their structure. DODAC also gave the system a positive charge. To determine the solubilization capacity, the dyes 1-Naphthol, Sudan Red G and Oil Red O were used. For sample preparation two methods were used, spontaneous and direct solubilization. The measurement was performed after 1, 2, 3 and 7 days from the preparation of the samples by UV-VIS spectrophotometry. The solubilization capacity was determined from the measured absorbance by calculation from the calibration curves. The results indicate that direct solubilization is slightly more effective than spontaneous solubilization. Of the selected dyes, 1-Naphthol is the substance with the smallest molecule, and therefore it seems to be 100% solubilized in the vesicle system.
|
guest ::
