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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
The role of humoral factors in the snail immune response against schistosomes
 Košťáková, Monika ; Horák, Petr (advisor) ; Dvořák, Jiří (referee)
Digenetic trematodes such as Schistosoma mansoni use molluscs, mainly Gastropoda in their life cycle, as their intermediary hosts. e internal defense system (IDS) of snails is composed of immune cells called hemocytes, which are the main effectors and act jointly with soluble components. Humoral factors could in uence directly the parasite's larval stage, the activity of hemocytes and also may serve in recognition of the parasite. Lectins are considered to be the main component of humoral immunity. ey have a primary role in non-self recognition. Other protein group with lectin-like activity called FRePs was found in Biomphalaria glabrata. eir unique structure contains a brinogen and an immunoglobulin-like domain. Cytokine-like molecules may play very important role in defense as well. Many molecules are present in hemolymph and their levels change during infection. e response to parasitosis is therefore very complex and still awaits further clari cation.
Detailed record
The role of humoral factors in the snail immune response against schistosomes
 Košťáková, Monika ; Dvořák, Jiří (referee) ; Horák, Petr (advisor)
Digenetic trematodes such as Schistosoma mansoni use molluscs, mainly Gastropoda in their life cycle, as their intermediary hosts. e internal defense system (IDS) of snails is composed of immune cells called hemocytes, which are the main effectors and act jointly with soluble components. Humoral factors could in uence directly the parasite's larval stage, the activity of hemocytes and also may serve in recognition of the parasite. Lectins are considered to be the main component of humoral immunity. ey have a primary role in non-self recognition. Other protein group with lectin-like activity called FRePs was found in Biomphalaria glabrata. eir unique structure contains a brinogen and an immunoglobulin-like domain. Cytokine-like molecules may play very important role in defense as well. Many molecules are present in hemolymph and their levels change during infection. e response to parasitosis is therefore very complex and still awaits further clari cation.
Detailed record

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