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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Changes in elemental distribution of rat liver tissue associated with myocardial fibrosis using LA-ICP-MS
 Štrenclová, Eliška ; Zlámalová Gargošová, Helena (referee) ; Vašinová Galiová, Michaela (advisor)
Myocardial fibrosis is a pathological condition characterized by excessive accumulation of extracellular matrix in cardiac tissue, resulting in impaired cardiac function and potentially serious cardiovascular complications. However, recent studies suggest that myocardial fibrosis may affect not only cardiac tissue but also other organs such as the liver. The aim of this bachelor thesis was to investigate changes in the elemental distribution of liver tissue from healthy individuals by comparing the elemental distribution of liver tissue from individuals with myocardial fibrosis using the LA-ICP-MS method. When comparing the distribution maps of the control and experimental groups, changes were observed mainly in the distribution of iron isotopes; therefore, particular attention was later paid to it. The results of this research may contribute significantly to a better understanding of the relationship between myocardial fibrosis and liver tissue, and the knowledge gained may help to develop new diagnostic approaches.
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Intraoperative 3D x-ray during internal fixation of fractures and its comparison with 2D radiographs.
 ANTONÍNOVÁ, Eva
The aim of the work is evaluation of the use of a mobile skiascopic device equipped with 3D technology used in the traumatologic operating room of Znojmo Hospital during osteosynthesis in the wrist and knee area. To compare the quality of fracture reposition and fixation, measuring the position of the adjacent articular surface to the axial radium position and to the axial tibia position in the second area was made. The study also discusses skiascopic planar doses and compares the difference between 2D and 3D imaging techniques. The following mean values were determined in the sample diameter, median, modus and maximal / minimal age of patients was calculated. Further, variance and standard deviation of the sample were determined by using PC Excel programme. The surveyed values were graphed. The study also deals with the length of skiascopy during the fracture osteosynthesis at 2D and 3D imaging technologies. The values obtained from the monitors were statistically analyzed and compared by a two-selective test. The devices are equipped with a DAP metre, which provides quantitative information about the planar radiation dose applied to the patient. Acquired information about the planar radiation dose (DAP) at the both techniques were statistically analyzed and compared by the two-selective test. The work was compared with studies of some other authors dealing with the same issue. Our analysis did not confirm greater contribution of 3D imaging technology to the reposition and fixation of intra-articular fractures from the radiological point of view.
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