|
|
Manufacturing Processes Management with Usage of Simulation Tools
Richtr, Jiří ; Karpeta, Vladimír (referee) ; Šunka, Josef (advisor)
Simulace výrobních procesů pomáhá optimalizovat výrobu, logistiku a další systémy, díky čemuž dochází ke snižování nákladů a racionalizaci vnitropodnikových procesů. Využitím diskrétní simulace programu Witness Power with Ease se v diplomové práci optimalizuje logistický tok materiálu ve společnosti Hella Autotechnik, s.r.o. Práce přibližuje metody a jednotlivé fáze tvorby modelu včetně jeho validace a navrhuje vylepšení, díky kterému by mělo dojít ke snížení nákladů na dopravní služby o 24 400 Kč měsíčně.
|
|
|
Ischemia of free flaps
Richtr, Patrik ; Vodička, Josef (advisor) ; Sukop, Andrej (referee) ; Veselý, Jiří (referee)
Background: Free muscle flap transfers, frequently used in plastic and reconstructive surgery, are associated with alternating episodes of ischemia and reperfusion. This phenomenon could be a cause of damage in the transferred flap. Major detrimental effect is usually attributed to the oxidative stress. Aim: The aim of this study was therefore 1) to develop a clinically relevant experimental model of free muscle flap for musculus latissimus dorsi (MLD), 2) to elaborate a technique allowing, by means of routine laboratory methods, the detection of changes occurring with oxidative stress, and 3) to evaluate the impact of ischemia and subsequent reperfusion on free flap muscle tissue (in terms of oxidative stress). Methods: In 18 domestic pigs, MLD was prepared on both sides (experimental and control), leaving just the thoracodorsal branch for nutrition. The vascular stalk for the experimental MLD was clamped temporarily (60 min) to mimic ischemia during flap transfer. After the clamp release (corresponds to reperfusion following anastomosis), both arterial, venous blood, and tissue samples were obtained from the ischemic as well as control flaps at timepoints 1, 30, 45, and 60 min. For baseline characteristics, tissue, arterial, and venous blood were sampled prior to clamping. In all samples, lactate,...
|
|
|
Ischemia of free flaps
Richtr, Patrik ; Vodička, Josef (advisor) ; Sukop, Andrej (referee) ; Veselý, Jiří (referee)
Background: Free muscle flap transfers, frequently used in plastic and reconstructive surgery, are associated with alternating episodes of ischemia and reperfusion. This phenomenon could be a cause of damage in the transferred flap. Major detrimental effect is usually attributed to the oxidative stress. Aim: The aim of this study was therefore 1) to develop a clinically relevant experimental model of free muscle flap for musculus latissimus dorsi (MLD), 2) to elaborate a technique allowing, by means of routine laboratory methods, the detection of changes occurring with oxidative stress, and 3) to evaluate the impact of ischemia and subsequent reperfusion on free flap muscle tissue (in terms of oxidative stress). Methods: In 18 domestic pigs, MLD was prepared on both sides (experimental and control), leaving just the thoracodorsal branch for nutrition. The vascular stalk for the experimental MLD was clamped temporarily (60 min) to mimic ischemia during flap transfer. After the clamp release (corresponds to reperfusion following anastomosis), both arterial, venous blood, and tissue samples were obtained from the ischemic as well as control flaps at timepoints 1, 30, 45, and 60 min. For baseline characteristics, tissue, arterial, and venous blood were sampled prior to clamping. In all samples, lactate,...
|
|
|
Manufacturing Processes Management with Usage of Simulation Tools
Richtr, Jiří ; Karpeta, Vladimír (referee) ; Šunka, Josef (advisor)
Simulace výrobních procesů pomáhá optimalizovat výrobu, logistiku a další systémy, díky čemuž dochází ke snižování nákladů a racionalizaci vnitropodnikových procesů. Využitím diskrétní simulace programu Witness Power with Ease se v diplomové práci optimalizuje logistický tok materiálu ve společnosti Hella Autotechnik, s.r.o. Práce přibližuje metody a jednotlivé fáze tvorby modelu včetně jeho validace a navrhuje vylepšení, díky kterému by mělo dojít ke snížení nákladů na dopravní služby o 24 400 Kč měsíčně.
|
|
|
Concentrations and forms of phosphorus in the runoff from small agricultural catchments in the catchment of Orlík Reservoir
Richtr, J. ; Hejzlar, Josef ; Semančíková, E.
Concentrations of major P forms were monitored in the runoff from 21 small agricultural catchments with dominant arable land or grassland within the basin of Orlík Reservoir during one seasonal cycle. Mean concentrations of dissolved reactive P (DRP) and dissolved non-reactive P (DNP) were low and not differed at the arable land and grassland catchments (DRP 32 and 24 μg/l, DNP 8 and 9 μg/l, respectively). Particulate P (PP) concentrations varied significantly between these two types of catchments (77 and 20 μg/l, respectively). Apparently, PP did not originated from recent erosion of land surface but from sediment resuspension or bank erosion in streams. Significant relationships between P concentrations in oxalate extracts of upper (0–15 cm) and deep (50–70 cm) soil layers and between the phosphate saturation index in the 50–70 cm soil layer and the DRP concentration in runoff demonstrated existence of relationship between soil available P and P concentration in catchment runoff.
|
|
| |
|
| |
|
| |
guest ::
RSS feed.