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Treatment of recurrent chronic wound.
Nagyová, Lucie ; Semecký, Vladimír (advisor) ; Šimkovič, Dušan (referee)
Lucie Nagyová Treatment of recurrent chronic wound Diplomová práce Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Studijní obor: Farmacie The aim of this work is understanding to recurrent chronic wound healing processes, with a view to chronic diabetic foot ulcer (DFU) and ways of its treatment. The purpose is to find, how treatment of chronic DFU is conducted in current clinical practise and then compare this finding with theory. We chose a group of twenty patiens incidentally, and we made a brief analysis of chronic DFU treatment based on information taken from patients' health reports. We found that the treatment is combinated and mostly local with using wild range of wound contact layers. The contact layer and the way of treatment are chosen individually, according to a type of a defect and a patient's health state. New ways of treatment targeted to molecular levels of healing wound are not used in current clinical practise because majority of patients can not afford this too expensive therapy. Because of that thorough education of patients is necessary.
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Metabolic Syndrome -Changing Profile of Risks
Nagyová, Lucie ; Semecký, Vladimír (advisor) ; Herink, Josef (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Mgr. Lucie Nagyová Consultant: doc. RNDr. Vladimír Semecký, CSc. Metabolic Syndrome - Changing Profile of Risks Rigorous work The aim of this work is to discover how hypolipidemic statine treatment changes lipid spektrum and other laboratory markers in patients. And to discover how metformine treatment influences levels of glycated hemoglobine and glycemia. Patients taking statins were compared according to a type of statin they have had to simvastatine - Simvor® group and atorvastatine - Atoris® group. We did not manage to prove positive effect of hypolipidemic treatment to laboratory markers. However, atorvastatine group had lower lipid levels than simvastatine group. Patients taking metformine had lower glycemia, lower glycated hemoglobine and lower CRP levels. Next testing of larger and more homogenic group is necessary.
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Metabolic Syndrome -Changing Profile of Risks
Nagyová, Lucie ; Semecký, Vladimír (advisor) ; Herink, Josef (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biological and Medical Sciences Mgr. Lucie Nagyová Consultant: doc. RNDr. Vladimír Semecký, CSc. Metabolic Syndrome - Changing Profile of Risks Rigorous work The aim of this work is to discover how hypolipidemic statine treatment changes lipid spektrum and other laboratory markers in patients. And to discover how metformine treatment influences levels of glycated hemoglobine and glycemia. Patients taking statins were compared according to a type of statin they have had to simvastatine - Simvor® group and atorvastatine - Atoris® group. We did not manage to prove positive effect of hypolipidemic treatment to laboratory markers. However, atorvastatine group had lower lipid levels than simvastatine group. Patients taking metformine had lower glycemia, lower glycated hemoglobine and lower CRP levels. Next testing of larger and more homogenic group is necessary.
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Treatment of recurrent chronic wound.
Nagyová, Lucie ; Šimkovič, Dušan (referee) ; Semecký, Vladimír (advisor)
Lucie Nagyová Treatment of recurrent chronic wound Diplomová práce Univerzita Karlova v Praze, Farmaceutická fakulta v Hradci Králové Studijní obor: Farmacie The aim of this work is understanding to recurrent chronic wound healing processes, with a view to chronic diabetic foot ulcer (DFU) and ways of its treatment. The purpose is to find, how treatment of chronic DFU is conducted in current clinical practise and then compare this finding with theory. We chose a group of twenty patiens incidentally, and we made a brief analysis of chronic DFU treatment based on information taken from patients' health reports. We found that the treatment is combinated and mostly local with using wild range of wound contact layers. The contact layer and the way of treatment are chosen individually, according to a type of a defect and a patient's health state. New ways of treatment targeted to molecular levels of healing wound are not used in current clinical practise because majority of patients can not afford this too expensive therapy. Because of that thorough education of patients is necessary.
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