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National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Monitoring of Pleural Effusion Parameters During the Treatment of Chest Empyema
 Matuchová, Inka ; Krejsek, Jan (advisor) ; Bobek, Vladimír (referee) ; Vodička, Josef (referee)
Monitoring of pleural effusion parameters during the treatment of chest empyema Chest empyema is a severe complication with collection of pus in the pleural cavity. The mortality rate of chest empyema is up to 40 %. Generally, treatment involves a drain insertion into the inflammatory focus and pleural space irrigation with local application of medication. These processes are usually lengthy with high risk of relapse. Our aim is to shorten the period of treatment using cytological-energy analysis of pleural effusions. This approach is based on simultaneous cytological and metabolic investigation of the pleural effusions. Results allow us to determine the type and intensity of local immune response in the pleural cavity. Repetitive investigations of pleural effusions in time give us information aiming the development of local immunity response in the pleural cavity and can follow the effect of therapy. Our goal is to define the theoretical framework for application of cytological-energy analysis of pleural effusions in patients with chest empyemas. The determination of the catalytic activities of aspartate aminotransferase (AST) and lactate dehydrogenase (LDH) in pleural effusions as parameters of tissue damage is introduced by us. We established that cytological-energy analysis of pleural effusion...
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