|
|
Analysis of antibiotic administration in prophylaxis I.
Domecký, Petr ; Malý, Josef (advisor) ; Matoulková, Petra (referee)
8 Abstract Analysis of antibiotic administration in prophylaxis I Author: Petr Domecký Tutor: PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Lucie Hauschke, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Antibiotic prophylaxis (AP) plays an important role in reduction of surgical site infection (SSI). It is the administration of an eligible antibiotic or chemotherapeutic (ATB) in a single dose, usually 30 minutes before surgery, followed by two to three doses during or after the surgery, regarding the selected ATB and the surgical procedure. The aim of this work was to analyse the AP in surgical procedures at the Masaryk Hospital in Ústí nad Labem (MNUL) in the context of the MNUL guideline (DP) and the research on available AP work. Methods: A cross-sectional observational study ran from January 2018 to March 2018 in surgical departments at MNUL. The study included patients aged ≥ 18 years who underwent surgery in a defined period (5 February 2018 to 9 February 2018) and gave their consent to the study. The practicability of the study was verified by a pilot part. Initially, a research of published studies concerning AP was carried out which provided outputs for AP establishment (PPA). Subsequently, a form for...
|
|
|
Analysis of antibiotic administration in prophylaxis I.
Domecký, Petr ; Malý, Josef (advisor) ; Matoulková, Petra (referee)
8 Abstract Analysis of antibiotic administration in prophylaxis I Author: Petr Domecký Tutor: PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Lucie Hauschke, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Antibiotic prophylaxis (AP) plays an important role in reduction of surgical site infection (SSI). It is the administration of an eligible antibiotic or chemotherapeutic (ATB) in a single dose, usually 30 minutes before surgery, followed by two to three doses during or after the surgery, regarding the selected ATB and the surgical procedure. The aim of this work was to analyse the AP in surgical procedures at the Masaryk Hospital in Ústí nad Labem (MNUL) in the context of the MNUL guideline (DP) and the research on available AP work. Methods: A cross-sectional observational study ran from January 2018 to March 2018 in surgical departments at MNUL. The study included patients aged ≥ 18 years who underwent surgery in a defined period (5 February 2018 to 9 February 2018) and gave their consent to the study. The practicability of the study was verified by a pilot part. Initially, a research of published studies concerning AP was carried out which provided outputs for AP establishment (PPA). Subsequently, a form for...
|
|
|
The analysis of eating habits of diabetics in the USA
Vaňkátová, Helena ; Vlček, Jiří (advisor) ; Matoulková, Petra (referee)
Besides the good drug compliance, appropriate nutrition plays important role in successful management of the metabolic aspects of type 2 diabetes mellitus (DM2), and in the prevention of diabetes-related conditions. The goal of this study was to analyze eating habits among DM2 patients in the United States. The Fat- and Fiber-Related Diet Habits Questionnaire (A.Shattuck, 1998) was used in this study to obtain identical data for comparison. The original version was slightly adjusted according to the local habits. The study took place at the El Rio Community Health Center clinics in Tucson, Arizona, USA; during the time period of three months (September to December 2011). Patients with DM2 patients visiting the clinic were recruited for participation. Once patients were given the questionnaire, answers were put into the database created in an Excel application (Microsoft Office 2010) and analyzed using the frequency analysis. 207 patients filled out the questionnaire. The mean age was 56,8 ± 12,6 years, the mean age when diagnosed with DM2 was 45,3 ± 12,7 years, BMI 33,2 ± 7,8 kg/m2, the mean waist circumference 109,7 ± 19,7 cm and the mean A1C was 8,1± 1,7% (ad DCCT). 10% of participants were treated only by the diet, 49% with peroral antidiabetics (PAD), 14% with insulin, and 28% with combination...
|
|
|
The Importance of Self-Reported Medication Adherence in the Evaluation of the Effectiveness of Pharmacotherapy
Ládová, Kateřina ; Matoulková, Petra (advisor) ; Červený, Petr (referee) ; Lukáš, Milan (referee) ; Kolář, Jozef (referee)
Charles University in Prague, Faculty of Pharmacy in Hradec Králové Department of Social and Clinical Pharmacy Candidate: Mgr. Kateřina Ládová Supervisor: PharmDr. Petra Matoulková, Ph.D.; PharmDr. Magda Vytřísalová, Ph.D. (Consultant) Title of Doctoral Thesis: The Importance of Self-Reported Medication Adherence in the Evaluation of the Effectiveness of Pharmacotherapy Introduction and Objective: Medication adherence (MA) is a highly variable factor affecting the response to the therapy. Especially in chronic disease, non-adherence presents a problem that may have health, social, and even economic consequences. Measuring MA is the most often performed by self-reported surveys which enables, among others, their simple application in research as well as in every day clinical practices. Self-reported MA monitoring may contribute to maximizing the effectiveness of pharmacotherapy and minimizing the risk of therapy failure, however, standardization of measuring process is needed. Moreover, some factors such as healthy adherer effect (HAE), which reflect patient health seeking behaviour but cannot be easily monitored, can favourably affect health outcomes. Acquired results may then be incorrectly attributed to drug therapy examined in the study. Hence, the main aims of this doctoral thesis were: 1) to...
|
|
|
Risk of skin cancer and lymphoproliferative diseases in patients after kidney transplantation
Sidorová, Kristína ; Malý, Josef (advisor) ; Matoulková, Petra (referee)
Risk of skin cancer and lymphoproliferative diseases in patients after kidney transplantation Author: Kristína Sidorová Tutor: doc. PharmDr. Josef Malý, Ph.D. Consultant: Mgr. Barbora Vaňková Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Organ transplantations (Tx) are associated with the lifelong use of immunosuppressive therapy (IS), which carries with it, among other risks, an increased incidence of malignancies. The most common malignancies after Tx are skin tumors, post-transplant lymphoproliferative diseases (PTLD) are also more common in transplant patients. The aim of the study was to determine the incidence of skin tumors and PTLD in patients with kidney Tx within one transplant center and to analyze the risk factors associated with these diseases. Methods: Retrospective longitudinal study was conduted in the Teaching Hospital Hradec Králové. The study included patients from the age of 18 who had overcome kidney Tx until 24 April 2019, were registered in a transplant clinic in Hradec Králové and had a medical record in the hospital information system. Data collection from medical records took place from 15 April 2019 to 31 December 2019. Collected data included demographic characteristics, family history,...
|
|
|
Attitudes towards treatment and knowledge of hormonal contraceptive users
Fufaľová, Veronika ; Malá, Kateřina (advisor) ; Matoulková, Petra (referee)
Diplomová práca Postoje k liečbe a znalosti užívateliek hormonálnej antikoncepcie Abstract Attitudes towards treatment and knowledge of hormonal contraceptive users Author: Veronika Fufaľová¹ Supervisor: PharmDr. Kateřina Ládová, Ph.D.¹ Consultant: PharmDr. Anna Oleárová, PhD., MPHš ¹Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic šDepartment of Organisation and Management of Pharmacy, Faculty of Pharmacy, Comenius University in Bratislava, Slovak Republic Introduction: Hormonal contraception (HC) is popular and a reliable birth control method. Its use is although associated with some risks and many myths or misconceptions. Objective: The aim of this thesis was to determine the attitudes towards treatment and awareness of HC risks of its users in regard to various types and application forms in specific region by means of anonymous questionnaire. Methods: The research was carried out as a prospective questionnaire survey. Anonymous questionnaires consisted of 35 questions divided into 6 sections to obtain sociodemographic data, information concerning HC users and their form of HC, information about the extent of knowledge concerning gynaecological examination, HC risks and HC misconception awareness. One part of questionnaire was focused...
|
|
|
Drug Information Centre service analysis III.
Harazimová, Tereza ; Malá, Kateřina (advisor) ; Matoulková, Petra (referee)
Drug Information Centre service analysis III. Author: Tereza Harazimová Supervisor: PharmDr. Kateřina Malá, Ph.D. Consultant: PharmDr. Petra Rozsívalová Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction: Drug Information Center (DIC) of the Faculty of Pharmacy in Hradec Králové, Charles University, and University Hospital Hradec Králové was established in 1994. Major activity of the DIC is providing expert information about drugs - primarily in the form of answers to various medicines-related enquiries sent by healthcare professionals. DIC deals with enquiries related to general pharmacotherapy including complementary and alternative medicine (CAM). Aim of study: Aim of the study was to evaluate DIC's activity in the period 2015-2017 through feedback from questioners and to analyse enquiries related to CAM in the period 1994-2017. Methods: The feedback of questioners whosent the enquiry to DIC from 2015 to 2017 was obtained using an online questionnaire containing 18 items - sociodemographic data and awareness of DIC, quality of answers to enquiries, satisfaction with provided services and lastly resolving of CAM related issues in practice. Furthermore, analysis of DIC's database in the period 1994-2017 was performed....
|
|
|
Drug Information Centre service analysis II.
Čikovská, Natália ; Malá, Kateřina (advisor) ; Matoulková, Petra (referee)
Drug Information Centre service analysis II. Author: Natália Čikovská Supervisor: PharmDr. Kateřina Malá, Ph.D. Consultant: PharmDr. Petra Thomson Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction: Drug Information Centre (DIC) of the Faculty of Pharmacy in Hradec Kralové was established in 1994 and is the only university-based DIC in the Czech Republic. DIC is providing expert information about drugs, such as answering medicines-related enquiries received from healthcare professionals. Objective: The objective of diploma thesis was to gather and analyze information about the informational service of LIC FAF UK a FN HK in 1994-2016 aimed for general characteristics of drug enquiries and professional drug information resources used for solving the enquiries. Methods: Detailed analysis of DIC activities was performed to compile suitable data. All enquiries from years between 1994 and 2016 were summarized into a database using Microsoft Excel software. General characteristics of the enquiries were analyzed, such an average number of enquiries per year or time needed for resolving one enquiry. Information about enquirers was considered as well, e.g. their profession and region, from which the enquiries were sent....
|
|
|
Drug Information Centre service analysis II.
Čikovská, Natália ; Malá, Kateřina (advisor) ; Matoulková, Petra (referee)
Drug Information Centre service analysis II. Author: Natália Čikovská Supervisor: PharmDr. Kateřina Malá, Ph.D. Consultant: PharmDr. Petra Thomson Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University, Czech Republic Introduction: Drug Information Centre (DIC) of the Faculty of Pharmacy in Hradec Kralové was established in 1994 and is the only university-based DIC in the Czech Republic. DIC is providing expert information about drugs, such as answering medicines-related enquiries received from healthcare professionals. Objective: The objective of diploma thesis was to gather and analyze information about the informational service of LIC FAF UK a FN HK in 1994-2016 aimed for general characteristics of drug enquiries and professional drug information resources used for solving the enquiries. Methods: Detailed analysis of DIC activities was performed to compile suitable data. All enquiries from years between 1994 and 2016 were summarized into a database using Microsoft Excel software. General characteristics of the enquiries were analyzed, such an average number of enquiries per year or time needed for resolving one enquiry. Information about enquirers was considered as well, e.g. their profession and region, from which the enquiries were sent....
|
|
|
Analysis of antibiotic administration in prophylaxis I.
Domecký, Petr ; Malý, Josef (advisor) ; Matoulková, Petra (referee)
8 Abstract Analysis of antibiotic administration in prophylaxis I Author: Petr Domecký Tutor: PharmDr. Josef Malý, Ph.D. Consultant: PharmDr. Lucie Hauschke, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and aims: Antibiotic prophylaxis (AP) plays an important role in reduction of surgical site infection (SSI). It is the administration of an eligible antibiotic or chemotherapeutic (ATB) in a single dose, usually 30 minutes before surgery, followed by two to three doses during or after the surgery, regarding the selected ATB and the surgical procedure. The aim of this work was to analyse the AP in surgical procedures at the Masaryk Hospital in Ústí nad Labem (MNUL) in the context of the MNUL guideline (DP) and the research on available AP work. Methods: A cross-sectional observational study ran from January 2018 to March 2018 in surgical departments at MNUL. The study included patients aged ≥ 18 years who underwent surgery in a defined period (5 February 2018 to 9 February 2018) and gave their consent to the study. The practicability of the study was verified by a pilot part. Initially, a research of published studies concerning AP was carried out which provided outputs for AP establishment (PPA). Subsequently, a form for...
|
guest ::
