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Mucocutaneous candidiasis and women's sexual hormones
Košťálová, Marie ; Tošner, Jindřich (advisor) ; Kudela, Milan (referee) ; Mencl, Karel (referee)
The aim of this work was to study relationship between mucocutaneous candidiasis (MCC) and women's sexual hormones. This problem is usually solved by dermatologists, gynaecologists and mycologists separately. Our approach is original, because it is primarily based on skin and/or cutaneous appendagies affection and searches for possible coincidence or other relation in vulvovaginal region. We examined 81 women in our study and divided them into two groups according to hormone-level investigation (women in fertile and perimenopausal period, women in postmenopausal period). We also developed "Candida" questionnaire for further anamnestic data correlation. The relationship between MCC and women's sexual hormones was studied both, in vivo and in vitro. We found C. albicans in vagina in both studied groups most frequently at the time of cutaneous candidiasis. In postmenopausal period the incidence of vaginal C. albicans was significantly lower (significantly lower levels of E2, PG). The cultivation identity between skin and vulvovaginal region was more frequent in fertile and perimenopausal period than in postmenopausal one, too. Predominantely concerned C. albicans again, the conformity was considerable in women with established ovulation (significantly higher levels of PG). In presence of C. albicans in...
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Impact of chlamidia trachomatis infection on chronic pelvic pain
Kříž, Jaroslav Thierry ; Košťál, Milan (advisor) ; Kudela, Milan (referee) ; Bouda, Jiří (referee)
Summary: Impact of Chlamydia trachomatis infection on chronic pelvic pain. The aim of the study was to determine whether women with chronic pelvic pain and Chlamydia infection differ from women with chronic pelvic pain without Chlamydia infection in respect of findings on laparoscopy and sexual behaviour. In a study conducted from April 2006 to December 2009, we monitored a group of 129 female patients suffering from chronic pelvic pain of more than 6 months duration. All monitored patients underwent laparoscopy, and during the procedure, swabs were taken from their Fallopian tubes and cervix, which were immunofluorescensed for the presence of Chlamydia trachomatis antigen. The patients were divided into two groups (Chlamydia positive and Chlamydia negative) according to the presence of Chlamydia antigen. The patients completed questionnaires covering the age at first sexual intercourse, number of lifetime and current sexual partners, frequency of sexual intercourse and the method of contraception. The differences in findings on laparoscopy and questionnaire results of women with positive and negative proof of Chlamydia infection were studied. Fisher's exact test was used for data description and group differences analysis. We observed that 30,2% (n=39) of a cohort of 129 women with chronic pelvic pain were...
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Impact of chlamidia trachomatis infection on chronic pelvic pain
Kříž, Jaroslav Thierry ; Košťál, Milan (advisor) ; Kudela, Milan (referee) ; Bouda, Jiří (referee)
Summary: Impact of Chlamydia trachomatis infection on chronic pelvic pain. The aim of the study was to determine whether women with chronic pelvic pain and Chlamydia infection differ from women with chronic pelvic pain without Chlamydia infection in respect of findings on laparoscopy and sexual behaviour. In a study conducted from April 2006 to December 2009, we monitored a group of 129 female patients suffering from chronic pelvic pain of more than 6 months duration. All monitored patients underwent laparoscopy, and during the procedure, swabs were taken from their Fallopian tubes and cervix, which were immunofluorescensed for the presence of Chlamydia trachomatis antigen. The patients were divided into two groups (Chlamydia positive and Chlamydia negative) according to the presence of Chlamydia antigen. The patients completed questionnaires covering the age at first sexual intercourse, number of lifetime and current sexual partners, frequency of sexual intercourse and the method of contraception. The differences in findings on laparoscopy and questionnaire results of women with positive and negative proof of Chlamydia infection were studied. Fisher's exact test was used for data description and group differences analysis. We observed that 30,2% (n=39) of a cohort of 129 women with chronic pelvic pain were...
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Mucocutaneous candidiasis and women's sexual hormones
Košťálová, Marie ; Tošner, Jindřich (advisor) ; Kudela, Milan (referee) ; Mencl, Karel (referee)
The aim of this work was to study relationship between mucocutaneous candidiasis (MCC) and women's sexual hormones. This problem is usually solved by dermatologists, gynaecologists and mycologists separately. Our approach is original, because it is primarily based on skin and/or cutaneous appendagies affection and searches for possible coincidence or other relation in vulvovaginal region. We examined 81 women in our study and divided them into two groups according to hormone-level investigation (women in fertile and perimenopausal period, women in postmenopausal period). We also developed "Candida" questionnaire for further anamnestic data correlation. The relationship between MCC and women's sexual hormones was studied both, in vivo and in vitro. We found C. albicans in vagina in both studied groups most frequently at the time of cutaneous candidiasis. In postmenopausal period the incidence of vaginal C. albicans was significantly lower (significantly lower levels of E2, PG). The cultivation identity between skin and vulvovaginal region was more frequent in fertile and perimenopausal period than in postmenopausal one, too. Predominantely concerned C. albicans again, the conformity was considerable in women with established ovulation (significantly higher levels of PG). In presence of C. albicans in...
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