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Analysis of interaction between cardiovascular signals using non-linear methods
Lokaj, Jiří ; Ronzhina, Marina (referee) ; Kolářová, Jana (advisor)
The short-term regulation of blood pressure is influenced by many influences, some being represented by cardiovascular signals and their changes. Because of the complexity of this system, the linear methods for its analysis are not sufficient. Non-linear methods for time series analysis have been devised quite a lot. In the course of this work, the analysis of the relations of several signals was evaluated as the most suitable conditional entropy and the resulting indexes of affinity and directionality. This method was applied to a set of heart-rate signals and systolic and diastolic pressure signals measured on eight adults and nine children. Relationships were analyzed but unfortunately after the statistical test was held the expected information links between the individual signals were not established. The indices were very small - in the hundredths of bits. Finally, optimization of the algorithm of the whole method has been performed and the newly modified function already shows significantly better results, for example strong information binding from the time-series of systolic pressure to a series of diastolic pressures.
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EMG biofeedback
Sekera, Lukáš ; Kolářová, Jana (referee) ; Janoušek, Oto (advisor)
First part of bachelor’s thesis is describing composition and function of muscles. Afterwards is described EMG signal, its measurement and evaluation. In the second part of bachelor’s thesis ale programed 3 games for myofeedback, which are using the evaluation of EMG signal. First parameter used is the duration of action potencial, second is strenghth of the muscle and last is measuring the time of response to stimulus.
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Radiotherapy
Šipka, Petr ; Janoušek, Oto (referee) ; Kolářová, Jana (advisor)
The goal of this thesis is to familiarize readers with the basics of the problem of electromagnetic and ionizing radiation, with its effects on a biological tissues and with types of ionizing radiations used in a therapy. It deals with a medical procedures in therapy planning and with procedures during therapy itself. Part of this Bachelor’s thesis is an application Radiation Calculator processed in MatLab software. Application is modeling the resulting radiation field while setting various parameters.
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Influence of breathe to baroreceptor reflex
Humpolík, Tomáš ; Janoušek, Oto (referee) ; Kolářová, Jana (advisor)
This Master's thesis deals with the influence of breathe to baroreceptor reflex. The first chapter is focused on measuring of blood pressure, in reference to later used method. In the second part is detailed analysis and explanation of term baroreflex, relationship between frequency spectra of systolic blood pressure, heart rate and breathing, mechanisms of regulation of blood pressure and heart rate variability. Third chapter deals with possible ways, how to analyze data, which are needed for estimation of baroreflex sensitivity, analyze of heart rate variability and estimation of power spectral density. Next parts of this thesis is paid attention to technical equipment and methods of acqusition of data, using this equipmnent. Part of this work is also software application, which makes possible from the recorded data estimate baroreflex sensitivity.
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Computer-aided data quality monitoring and assessment in clinical research
Šiška, Branislav ; Kolářová, Jana (referee) ; Schwarz, Daniel (advisor)
The diploma thesis deals with the monitoring and evaluation of data in clinical research. Usual methods to identify incorrect data are one-dimensional statistical methods per each variable in the register. Proposed method enters directly into database and finds out outliers in data using machine learning combined with multidimensional statistical methods that transform all column variables of clinical register to one, representing one record of patient in the register. Algorithm of proposed method is written in Matlab.
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Analysis of EMG Signal for Prosthetic hand based on Fuzzy Logic Technique
Ollé, Tamás ; Kolářová, Jana (referee) ; Pathak, Pawan Kumar (advisor)
Lidská ruka je koncový orgán horní končetiny, který slouží k důležité funkci uchopení, stejně jako důležitý orgán pro vnímání a komunikaci. Je to úžasný příklad o tom, jak komplexní mechanismus může být implementovaný, schopný chápat velice komplexní a užitečné úkoly používáním velmi efektivní kombinace mechanismů, snímání a řídicích funkcí. Elektromyogram (EMG) byl původně vyvinutý pro vyšetrování svalnatého nepořádku. Klinické aplikace se brzo rozšířila, nejpozoruhodněji ve výzkumu epilepsii a nakonec se stal populární po zavedení protéz, specificky tělem poháněných protéz. EMG nahrávání je použito pro studování funkčního stavu svalu během různých pohybů. Cílem tohoto projektu je vyvinutí elektromyogramové (EMG) metody třídění, která bude pomáhat v aplikacích jako systém pracující v reálném čase. První část tohoto projektu bylo získávání informací. Údaje reálného času byly zaznamenaný pomocí EMG monitorovacího systému (BIOPAC) a kompletní datová sada různých osob byl zaznamena. Tyto EMG data byly konvertované ze souboru ASCII do čitelné formy pro MATLAB. Druhou částí projektu byla extrakce vlastností. Pět tradičních parametrických rysů bylo vypočítáno, jmenovitě Integrovaný EMG (IEMG), variance (VAR), Zero Crossing (ZC), Slope Sign Changes (SSC) a Vlnová délka (WL). Třetí část projektu byla klasifikace EMG vzorů s použitím fuzzy logiky. Výsledky jsou docela slibné.
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Alpha monitor
Svobodová, Eva ; Kolářová, Jana (referee) ; Chmelař, Milan (advisor)
The master´s thesis presents the problems of EEG biofeedback and its application to relax people. The first part discusses the properties of EEG signal , the requirements of the standard EEG and also distribusion signal into different frequency bands. The main essence of the work is the design and realization of Alfa Monitor – a device for relaxation , that for implamanting EEG biofeedback uses acoustic form and sensing of electrical activity of brain in the region of alpha waves. The second half of the work is t focused on circuit design, using integrated circuits with component values of relevant calculations . Further, it analyzes the practical implementation of alfa monitor. The last chapter is devoted to the testing the functionality of this device.
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Validaton of multichannel bioimpedance of vessels using synchronized vascular ultrasonography
Hidegová, Simona ; Kolářová, Jana (referee) ; Mézl, Martin (advisor)
The inclusion of a new device in clinical practice requires an adequate validation. The original publication which introduced multichannel bioimpedance monitor MBM was focused on discribing its technical parameters and demonstration measurements. Further evaluation desires comparision with other standard measuring device. This thesis describes pulse wave measurement by MBM and by other medical devices used for establishing cardiovascular risk. It proposes the validation experiment with synchronized vascular ultrasonography as a reference method. The process of the experimental measurement, aquired data and following data analysis are described in detail. The outputs of the experiment are statistically evaluated. The MBM’s performance and design of the experiment are discussed.
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Use of digital accelerometers in Linet bed controls
Dvořák, Ferdinand ; Sekora, Jiří (referee) ; Kolářová, Jana (advisor)
The subject of this bachelor thesis is a design of methods for accelerometer usage in medical bed controllers in order to eliminate the activation button. In the introduction the Linet company is presented and the issue of legislation and safety of controling the medical beds is briefly discussed. This part is followed by a theoretical chapter considering MEMS technology and accelerometers. The metodology of reference and simulative signals acquisition is designed. These signals are then analysed. In following chapters the particular methods of solutions are presented. The comparison of the presented methods and the final summary of the thesis is included in the conclusion.
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