Home > Search Results: Holštajn Zemánková, Petra
Search:
Search Tips :: Advanced Search
Search collections:
Sort by: Display results: Output format:
National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Multiple Sclerosis - Neuropsychological markers for monitoring disease activity
 Friedová, Lucie ; Uher, Tomáš (advisor) ; Holštajn Zemánková, Petra (referee) ; Libertínová, Jana (referee)
Multiple sclerosis (MS) is a chronic autoimmune disease of the central nervous system that generates a wide range of clinical symptoms. These include cognitive impairment, a set of symptoms closely associated with the quality of life, which also serves as one of the most important predictors of limited ability to work. This doctoral thesis presents the output from four studies divided into three areas focusing on neuropsychological markers in connection to other manifestations and effects of MS. The first researched area is the link between speech characteristics and the information processing speed by patients with MS. Our study has proven a profound association between lower speed of articulation and below-average performance in terms of information processing speed. We have proven that acoustic quantitative speech analysis has the potential to identify patients with below-average cognitive performance. Another goal of this doctoral thesis was to ascertain the predictive value of serum neurofilament light chain levels in recently diagnosed patients with MS for the development of cognitive disorder within nine years of observation. During the period of observation, we uncovered only a loose link between high levels at the onset of the disease and the deterioration of cognitive functions in...
Detailed record

Interested in being notified about new results for this query?
Subscribe to the RSS feed.
Digital Repository :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.2
Maintained by admin.invenio@techlib.cz
This site is also available in the following languages:
Česky  English