National Repository of Grey Literature 3 records found  Search took 0.00 seconds. 
Comparison between original and generic statin
Francová, Soňa ; Melicharová, Ludmila (advisor) ; Vokřál, Ivan (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Soňa Francová Supervisor: PharmDr. Ludmila Melicharová Title of diploma thesis: Comparison of the effects of original and generic statin One of the most common causes of death in the Czech Republic is cardiovascular disease. The treatment for the dyslipidaemia and the hyperlipoproteinemia is an apparent part of the primary as well as the secondary methods of prevention of the disease. A major break through in treatment was a discovery of the hypolipidemia group called statins fifteen years ago. The potential of statins is increasing due to continual discoveries of the extra-lipid effects which positively influence the yearly consummation of this substance. The research involves the comparison of the effects of the original medicament Zocor distributed by Merc & Co and the generic medicament Simgal produced by IVAX. The purpose of this work was to compare not only the efficiency of two medicaments but also their effectiveness on the level of cholesterol in the plasma. One year observations were implemented on two different groups with ten subjects in each group. The patients have been treated with the same dosage - 20 mg of medicament once a day. The research has been randomized,...
Comparison between original and generic statin
Francová, Soňa ; Vokřál, Ivan (referee) ; Melicharová, Ludmila (advisor)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmacology and Toxicology Candidate: Soňa Francová Supervisor: PharmDr. Ludmila Melicharová Title of diploma thesis: Comparison of the effects of original and generic statin One of the most common causes of death in the Czech Republic is cardiovascular disease. The treatment for the dyslipidaemia and the hyperlipoproteinemia is an apparent part of the primary as well as the secondary methods of prevention of the disease. A major break through in treatment was a discovery of the hypolipidemia group called statins fifteen years ago. The potential of statins is increasing due to continual discoveries of the extra-lipid effects which positively influence the yearly consummation of this substance. The research involves the comparison of the effects of the original medicament Zocor distributed by Merc & Co and the generic medicament Simgal produced by IVAX. The purpose of this work was to compare not only the efficiency of two medicaments but also their effectiveness on the level of cholesterol in the plasma. One year observations were implemented on two different groups with ten subjects in each group. The patients have been treated with the same dosage - 20 mg of medicament once a day. The research has been randomized,...

See also: similar author names
1 Francová, Simona
3 Francová, Soňa
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