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Detection of atrial fibrillation in short-term ECG
Ambrožová, Monika ; Janoušek, Oto (referee) ; Ronzhina, Marina (advisor)
Atrial fibrillation is diagnosed in 1-2% of the population, in next decades, it expects a significant increase in the number of patients with this arrhythmia in connection with the aging of the population and the higher incidence of some diseases that are considered as risk factors of atrial fibrillation. The aim of this work is to describe the problem of atrial fibrillation and the methods that allow its detection in the ECG record. In the first part of work there is a theory dealing with cardiac physiology and atrial fibrillation. There is also basic descreption of the detection of atrial fibrillation. In the practical part of work, there is described software for detection of atrial fibrillation, which is provided by BTL company. Furthermore, an atrial fibrillation detector is designed. Several parameters were selected to detect the variation of RR intervals. These are the parameters of the standard deviation, coefficient of skewness and kurtosis, coefficient of variation, root mean square of the successive differences, normalized absolute deviation, normalized absolute difference, median absolute deviation and entropy. Three different classification models were used: support vector machine (SVM), k-nearest neighbor (KNN) and discriminant analysis classification. The SVM classification model achieves the best results. Results of success indicators (sensitivity: 67.1%; specificity: 97.0%; F-measure: 66.8%; accuracy: 92.9%).
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Analysis of selected physiological parameters of athletes during exercise
Ambrožová, Monika ; Kolářová, Jana (referee) ; Ronzhina, Marina (advisor)
Regular sport activity is considered as neccessary part of our lifes. Sport is reccomended for preventing various diseases, enhancing immunity system or for controlling weight and for enhancing conditions. However, how severaly is sport activity benefit for human health and when it becomes harmful for it? This work deals with possible negative effects of strenous excercise on human organism. In our case it is ultra-maraton and mountbiking. In following parts of this work it is tried to explaine metabolic changes and influance of strenous excercise on immunological and biochemical parametres. The parameters immunoglobulin A, M, leukocytes, creatinine, sodium and potassium ions and enzymes such as lactatedehydrogenase, creatinekinase and alanineaminotransferase were studied. The values of these parameters were obtained from the blood samples taken before and after the race. A 23 samples from a 24-hour cycling race and 24 run-of-the-run race samples per 100 km were examined. A matlab tool was created for statistical analysis of data. A huge increase in the number of leukocytes was found in both types of races. In the MTB, it is an increase from 5.75 ± 1.29 x 109 / l to 11.80 ± 3.08 x 109 / l, in the race from 4.99 ± 1.84 x 109 / l to 13, 20 ± 5.36 x 109 / l. IgA did not significantly decrease, on the contrary slightly increased. IgM values have not changed significantly in runners. Cyclists experienced a statistically significant reduction in the original amount of 60.23 ± 6.54 mg / dl to 52.60 ± 10.43 mg / dl. There were statistically significant changes in CK and LDH levels in the race. From the original CK values of 4.25 ± 2.74 kat / l, the activity of the enzyme increased by 50.09 ± 60.08 kat / l due to the race. LDH is not significantly different in the cycling race as well as in the ALT enzyme. In this case, there was no statistically significant change to either type of race. Concentration of potassium and sodium ions decreased significantly. In potassium, its concentration dropped from 5.61 ± 0.59 mmol / l to 4.57 ± 0.39 mmol / l. Sodium ions dropped from 138.22 ± 1.17 mmol / l to 137.00 ± 1, 75 mmol / l.
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Detection of atrial fibrillation in short-term ECG
Ambrožová, Monika ; Janoušek, Oto (referee) ; Ronzhina, Marina (advisor)
Atrial fibrillation is diagnosed in 1-2% of the population, in next decades, it expects a significant increase in the number of patients with this arrhythmia in connection with the aging of the population and the higher incidence of some diseases that are considered as risk factors of atrial fibrillation. The aim of this work is to describe the problem of atrial fibrillation and the methods that allow its detection in the ECG record. In the first part of work there is a theory dealing with cardiac physiology and atrial fibrillation. There is also basic descreption of the detection of atrial fibrillation. In the practical part of work, there is described software for detection of atrial fibrillation, which is provided by BTL company. Furthermore, an atrial fibrillation detector is designed. Several parameters were selected to detect the variation of RR intervals. These are the parameters of the standard deviation, coefficient of skewness and kurtosis, coefficient of variation, root mean square of the successive differences, normalized absolute deviation, normalized absolute difference, median absolute deviation and entropy. Three different classification models were used: support vector machine (SVM), k-nearest neighbor (KNN) and discriminant analysis classification. The SVM classification model achieves the best results. Results of success indicators (sensitivity: 67.1%; specificity: 97.0%; F-measure: 66.8%; accuracy: 92.9%).
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Proverbs as a source of economic wisdom
Ambrožová, Monika ; Špecián, Petr (advisor) ; Máslo, Lukáš (referee)
In this bachelor thesis, I identify understanding of economic processes in folk proverbs. I judge folk proverbs from point of effectivity and their resemblance of reality. Effective rules should lead to desired purpose with low decision cost. I show that folk proverbs can be considered as representations of Hayek's spontaneous order. Prescriptive proverbs which are not contradicted by other proverbs are economically effective while descriptive proverbs criticize insufficiency of folk economics. These descriptive proverbs are consistent with observations of behavioural economy. Proverbs point out constant errors in human thinking. Folk proverbs contain a lot of economic wisdom and are thus appropriate area of interest for economists. I show that proverbial economics is rational and effective system as opposed to folk economics. With my thesis I contribute to study of proverbial economics which is almost unexplored.
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Analysis of selected physiological parameters of athletes during exercise
Ambrožová, Monika ; Kolářová, Jana (referee) ; Ronzhina, Marina (advisor)
Regular sport activity is considered as neccessary part of our lifes. Sport is reccomended for preventing various diseases, enhancing immunity system or for controlling weight and for enhancing conditions. However, how severaly is sport activity benefit for human health and when it becomes harmful for it? This work deals with possible negative effects of strenous excercise on human organism. In our case it is ultra-maraton and mountbiking. In following parts of this work it is tried to explaine metabolic changes and influance of strenous excercise on immunological and biochemical parametres. The parameters immunoglobulin A, M, leukocytes, creatinine, sodium and potassium ions and enzymes such as lactatedehydrogenase, creatinekinase and alanineaminotransferase were studied. The values of these parameters were obtained from the blood samples taken before and after the race. A 23 samples from a 24-hour cycling race and 24 run-of-the-run race samples per 100 km were examined. A matlab tool was created for statistical analysis of data. A huge increase in the number of leukocytes was found in both types of races. In the MTB, it is an increase from 5.75 ± 1.29 x 109 / l to 11.80 ± 3.08 x 109 / l, in the race from 4.99 ± 1.84 x 109 / l to 13, 20 ± 5.36 x 109 / l. IgA did not significantly decrease, on the contrary slightly increased. IgM values have not changed significantly in runners. Cyclists experienced a statistically significant reduction in the original amount of 60.23 ± 6.54 mg / dl to 52.60 ± 10.43 mg / dl. There were statistically significant changes in CK and LDH levels in the race. From the original CK values of 4.25 ± 2.74 kat / l, the activity of the enzyme increased by 50.09 ± 60.08 kat / l due to the race. LDH is not significantly different in the cycling race as well as in the ALT enzyme. In this case, there was no statistically significant change to either type of race. Concentration of potassium and sodium ions decreased significantly. In potassium, its concentration dropped from 5.61 ± 0.59 mmol / l to 4.57 ± 0.39 mmol / l. Sodium ions dropped from 138.22 ± 1.17 mmol / l to 137.00 ± 1, 75 mmol / l.
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