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National Repository of Grey Literature 4 records found  Search took 0.00 seconds. 
Synthetic study in the oxytocin field
 Hlaváček, Jan ; Slaninová, Jiřina ; Ragnarsson, U.
Isotopically labeled oxytocin with 13 C and 15 N in the C-terminal tripeptide part exhibited identical biological activity profile with the natural oxytocin.
Detailed record
Biologically inactive methylene-oxy analogs of oxytocin and vasopressin
 Mařík, Jan ; Buděšínský, Miloš ; Slaninová, Jiřina ; Hlaváček, Jan
Synthesis of two methylene-oxy pseudodipeptides H-Tyr.psi.[CH.sub.2./sub.O]Phe-OH and H-Tyr.psi.[CH.sub.2./sub.O]Ile-OH used for the synthesis of [Tyr.sup.2./sup..psi.[CH.sub.2./sub.O]Phe.sup.3./sup., Arg.sup.8./sup.]vasopressin and [Tyr.sup.2./sup..psi.[CH.sub.2./sub.O]Ile.sup.3./sup.]oxytocin respectively is presented.
Detailed record
Synthesis of methylene-oxy pseudodipeptides containing analogs of aspartic acid
 Mařík, Jan ; Hlaváček, Jan
Stereoselective synthesis of the orthogonally protected psudodipeptide H-Tyr(Bzl).psi.[CH2O]Asp(OtBu)-OH was carried out with an intention to use this building block in a construction of isosteric analogues of oostatic tetra- and pentapeptides.
Detailed record
Proline-rich peptides
 Hlaváček, Jan ; Mařík, Jan ; Bennettová, Blanka ; Tykva, Richard
Proline-rich peptides and proteins exhibits outstanding behaviour due to the cis-trans isomerism on Xaa-Pro bonds. An effect of cumulated proline residues on insect reproduction was studied in oostatic decapeptide and its shortened analogues with accelerated and enhanced oostatic activity.
Detailed record

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