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Perfusion Modelling in Optical Coherence Tomography
Štohanzlová, Petra ; Penhaker,, Marek (referee) ; Kudrna,, Petr (referee) ; Kolář, Radim (advisor)
This thesis deals mainly with perfusion modeling in optical coherence tomography (OCT). The introductory part deals with basic theory of the OCT, including a description of its basic applications. Part of the work was the testing of selected contrasting materials suitable for the OCT and the design and implementation of phantoms, which were subsequently used in the main part of the thesis. In the practical part, attention is paid to the perfusion analysis in the OCT, first the application of the dilution theory in the OCT for flow estimation, then a study testing the basic theory of perfusion on OCT by means of tissue phantom. Another part of the thesis is devoted to the method of speckle variance analysis for flow visualization.
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Multimodal retinal image registration
Štohanzlová, Petra ; CSc, Tomáš Suk, (referee) ; Harabiš, Vratislav (advisor)
This work deals with possibilities of registration of retinal images from different mo-dalities, concretely optical coherence tomography (OCT), scanning laser ophthalmoscopy (SLO) and fundus camera. In first stage is the interest focused on registration of SLO and fundus images, which will serve to determine area of interest for consecutive registration of OCT data. The final stage is finding correct location of OCT B-scans in fundus image. On the basis of the studied methods of registration was chosen method making use of computation of correlation coefficient for both cases. For finding optimal parameters of registration is used searching through whole space of parameters. In partial stages of the work was created algorithm for alignment of B-scans followed by detection of blood vessels and also simple algorithm for detection of blood vessels from fundus image. For more transparent registration the graphical user interface was created, which allows loading input images and displaying the result in several possible forms.
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Spirometry data analysis software
Rovná, Tereza ; Štohanzlová, Petra (referee) ; Harabiš, Vratislav (advisor)
This thesis is focused on the pulmonary function tests. The first part focuses on basic respiratory data, ventilation diseases and parameters of evaluation. The second part describes diagnostic methods in detail. These methods are used to obtain functional parameters of lung function, especially spirometry. The third part focuses on NI DAQ, spirometer´s probe, spirometer SPIROBANK, DT and spirometry data analysis software developed in LabVIEW 2013. The fourth part deals with comparison of results from my own spirometry data analysis software, spirometric probe and SPIROBANK DT.
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Specle analysis for optical coherence tomography image segmentation
Gallo, Vladimír ; Kolář, Radim (referee) ; Štohanzlová, Petra (advisor)
This paper presents basic principles of optical coherence tomography, review of applications and basic categorization of these systems. Paper also deals with the typical properties of images from optical coherence tomography, especially speckle pattern. This paper also provides an overview of the origin of speckle noise and utilization of its dependence on microstructure of probed tissue for image classification based on textural analysis. Experimental part of this paper consists of phantom preparation, data acquisition by OCT system, implementation of speckle analysis in MATLAB and of testing of its functionality on standard textural dataset and also on acquired image phantom data. Speckle analysis is used for phantom image data segmentation.
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Segmentation of retinal blood vessels in 3D images from optical coherence tomography
Žáková, Eliška ; Odstrčilík, Jan (referee) ; Štohanzlová, Petra (advisor)
The thesis deals with optical coherence tomography theory, eye and retinal structure and possibilities of retinal blood vessel segmentation in OCT scans. Further the segmentation of retinal layers used for blood vessels segmentation by OCTSEG application is shown. In the end 2D projections in the chosen layer of retinal blood vessels by different algorithms using mean, median, minimums and maximums in which are later segmented blood vessels are made and the results are compared. The best detection of blood vessels is in 2D projections made by algorithm using maximums. In the second case was better results of detection including background noise.
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Speckle noise reduction in images from optical coherence tomography
Sokol, Kamil ; Štohanzlová, Petra (referee) ; Kolář, Radim (advisor)
The thesis deals with speckle suppression in images acquired by optical coherence tomograph. It is divided into four parts. The first part describes basic information about the medical imaging method. It also deals with principle of measurement. The second section discusses the formation of image speckle and selected methods to reduce them. Next part is practical and consists of data acquisition, determination of the evaluation methodology and the implementation of speckle reduction methods. The last part is focused on testing and reviews of algorithms and discussion about their results.
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Phantom for measurement of flow rate using dilution methods
Botlová, Simona ; Štohanzlová, Petra (referee) ; Harabiš, Vratislav (advisor)
This bachelor thesis focuses on flow measurement by dilution method. To this end was constructed the product to measure a dilution curve. Part of the work is program developed in LabVIEW interface, which is able to capture data with Vernier pH probe connected via LabPro. Program is able to approximate the measured data and provides information about the area of interest. The paper also describes the dilution method, measurement of pH and model requirements. Based on the obtained results there was constructed laboratory task.
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ECG signal generator
Štohanzlová, Petra ; Sekora, Jiří (referee) ; Harabiš, Vratislav (advisor)
This work deals with the generation of ECG signal and options how to generate it using the LabVIEW program. On the basis of the studied methods of describing signal was chosen method making use of the similarity of the sections of ECG curve and the sinus respectively triangular pattern. This method was subsequently implemented in the LabVIEW environment. Created virtual instrument generates ECG signal in given heart rate and adjustable amplitude of waves. It is also possible to choose between 12 standard leads, to realize several failures of cardiac activity and various disturbance signals can be added to the signal. Signal can be sent to output or saved as a text file in real time in the specified format.
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Segmentation of choroid blood vessels in 3D images from optical coherence tomography
Maňkoš, Richard ; Kolář, Radim (referee) ; Štohanzlová, Petra (advisor)
This project deals with segmentation of choroid blood vessels in 3D images from optical coherence tomography. The first part is dedicated to theoretical description of the human eye. The second part describes basic information about the optical coherence tomography. In the third part two techniques, which are used on the blood vessels segmentation are described. The last part is practical and deals with an image processing in software OCTSEG and with own created algorithm for blood vessel segmentation.
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