National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Changes in brain magnetic resonance imaging in Alzheimer's disease
Šilhán, David ; Bartoš, Aleš (advisor) ; Dušek, Petr (referee) ; Krajčovičová, Lenka (referee)
Changes in brain magnetic resonance imaging in Alzheimer's disease Introduction Brain MRI is important auxiliary examination method in the diagnosis of Alzheimer's disease (AD). Mediotemporal atrophy is typical for late-onset AD. Brain atrophy can be different in patients with early-onset AD. Current visual scales for assessing brain atrophy in AD may be too complicated for routine clinical practice. Aims The main goal was to develop new, simple and reliable visual scales for the evaluation of mediotemporal and parietal atrophy on brain MRI, which will be suitable for the diagnosis of AD in routine clinical practice. Methods and patients We have developed a Parietal Atrophy Score (PAS) for the assessment of parietal atrophy, which is based on the evaluation of atrophy of 3 structures (sulcus cingularis posterior, precuneus, parietal gyri) on a sequence of coronal slices of the parietal lobe. We first used this scale to assess parietal cortex atrophy in 74 cognitively normal individuals from the Czech cohort (age range 48-87 years, MMSE 29 ± 1). The brain MRI of 25 people from this cohort were assessed by 4 evaluators with different professional experience to determine the reliability of the PAS. Parietal atrophy was compared between 24 patients with late-onset AD (MMSE 21 ± 3) and 26 cognitively normal...
How to make the process of purchase and supply chain in the Sunnysoft effective
Růžičková, Zuzana ; Jirsák, Petr (advisor) ; Šilhan, David (referee)
Master Thesis is focused on problems elimination and processes simplification in the purchase and supply chain of the company Sunnysoft. There were several solution variants suggested from which the best one was chosen and has been successfully applied in the company.

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1 Šilhán, David
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