Národní úložiště šedé literatury Nalezeno 2 záznamů.  Hledání trvalo 0.01 vteřin. 
Antimicrobial peptides isolated from the venom of wild bee Panurgus calcaratus
Čujová, Sabína ; Monincová, Lenka ; Slaninová, Jiřina ; Bednárová, Lucie ; Čeřovský, Václav
Three novel peptides designated as PNG-1, PNG-K and PNG-R were isolated from the venom of the solitary bee Panurgus calcaratus. They exhibited antimicrobial activity against Grampositive and -negative bacteria and fungi. In this work we focused on the characterization of PNG-R which is unique 25 amino acid residues and two disulfide bridges containing peptide. The secondary structure of PNG-R was studied by circular dichroism spectroscopy measured in water and in the presence of trifluoroethanol or sodium dodecyl sulfate.
Novel biologically active peptides from the venom of the solitary bee Macropis fulvipes (HYMENOPTERA: MELITTIDAE)
Monincová, Lenka ; Slaninová, Jiřina ; Voburka, Zdeněk ; Hovorka, Oldřich ; Fučík, Vladimír ; Borovičková, Lenka ; Bednárová, Lucie ; Buděšínský, Miloš ; Straka, J. ; Čeřovský, Václav
Two peptides (macropine-1 and macropin-2) were isolated, their structure determined by Edman degradation and mass spectrometry, which exhibited potent antimicrobial activity against both Gram-positive and -negative bacteria and moderate hemolytic activity against rat erythrocytes. We prepared several MAC-1 analogs to study the effect of their structure on antimicrobial and hemolytic activities.

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