Národní úložiště šedé literatury Nalezeno 1 záznamů.  Hledání trvalo 0.01 vteřin. 
Voltage clamp analysis of ajmaline-induced block of potassium currents in ventricular myocytes
Bahníková, M. ; Matějovič, P. ; Pásek, Michal ; Šimurdová, M. ; Šimurda, J.
This study was aimed to analyze the effects of the antiarrhythmic drug ajmaline (a known inhibitor of the fast sodium current INa) on the potassium currents, namely the transient outward current (Ito) and the current measured at the end of a depolarizing pulse (IK) in rat ventricular myocytes. Both currents were inhibited in concentration- and voltage-dependent manner. However, the effects were frequency-independent.

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