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BUT Technology Transfer Centre
Jabůrková, Dominika ; Svoboda, Jiří (referee) ; Nový, Alois (advisor) ; Novotný, Miloslav (advisor)
¨Bachelor thesis addresses the subject Technology Transfer Centre Brno - Královo pole- at Palacky hill in the technogy park Brno. TTC represents the institutional framework for the development and application of the results reserch at Brno University of Technology. It is also the contact point for companies interested in cooperation with the Technical University in the provided fields. The closest area is characterized by the proximity of different functions - universities, office spaces, space for light manufacturing, university colleges. The proposed building has four floors, simple monoblock, which replicates the shape of the land (trapezoid) is differentiated into 5 parts. These parts allow any hire parts of the object. The building have productions hall with private facilities, offices, laboratories and parking. The dominant feature is the entrance hall, which is glass and open. Entrance is framed with corteno sheet. In entrance hall is open staircase with corten banister, which is addressed in Part D in architectural detail. Supply object is behind the building, there are manipulating courts which are directly linked to the warehouses. The building is oriented mainly longitudinally - East west.
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Business Intelligence in the Laboratory
Musil, Jiří ; Novotný, Ota (advisor) ; Brůha, Jan (referee)
The main objective of this diploma thesis is the implementation of a pilot solution of Business intelligence in the laboratory company. This company is providing tests of samples of blood and urine. The diploma thesis is divided into two main parts. The first part contains theory. It describes the usage and components of the Business intelligence. Additionaly it describes the method Balanced scorecard and its usage in laboratory companies. The second part contains practical solution. At first there is a description of the company where is the solution implemented. In the next step the goals and metrics are determined on basis of the application of the method Balanced scorecard. The strategic map is created based on company goals. The last chapter contains a description of the implementation of the pilot solution and the description of created reports.
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Porovnání stability půdních agregátů na stejném půdním typu s rozdílnou intenzitou obhospodařování
Macháček, Vlastimil
This bachelor paper describes and interprets the research results of the comparison of soil aggregate stability. This comparison takes place in various localities with different farming intensity. The first part of the bachelor paper presents literary research, which closely depicts the main issues of this paper. Literary research also includes a technical description of the main issues of the bachelor paper and reflections of the authors who deal with this subject matter. The following part of the bachelor paper describes localities of Ořešín and Sobešiče, from which the soil samples for measuring were collected. This part also depicts climatic and soil conditions of these localities and sounding techniques. The paper describes in detail sampling and transport of the samples. The bachelor paper then depicts the methods of measurement and subsequent handling of the samples in the laboratory of soil mechanics LDF. In the following part of this paper the results are recorded and interpreted together with the commentaries on particular localities. Finally, the discussion about the research results, conclusion and bibliography follow. The bachelor paper is completed with photo documentation and graphs with the research results. These graphs are instrumental in clear arrangement of the results.
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The testing of celiac disease in connection with osteoporosis
SLADKÁ, Romana
My Bachelor´s thesis deals with the examination of celiac disease in connection to osteoporosis. The aim of the thesis was to specify the level of antidotes against tissue transglutaminase in the class IgA and IgG in the serum with osteoporosis diagnosed patients, to interpret, based on the results of the study, possible link between osteoporosis and celiac disease as well as to compare the outcome with scientific data. I focused on the present knowledge of osteoporosis and celiac disease in the first part. As for celiac disease, I described its history and characteristics. I also paid attention to diagnostics of celiac disease with the assistance of laboratory serological tests ELISA. I mentioned the free-gluten diet treatment after that. As regards osteoporosis, I described its history, symptoms, forms, perils and complications which the disease causes. I conducted the methodical part of my work in the biochemical haematological laboratory Stafila where I work, with its seat in České Budějovice. As for measurements, I took them in the department of microbiology, where immunologic tests are also taken. I carried out the screening of celiac disease from serum, namely the determination of antidotes against tissue transglutaminase in the class IgA and IgG, with the aid of ELISA - a sandwich method. I took measurements with 58 osteoporosis diagnosed patients. I obtained the sera thanks to the supervisor of my thesis Mrs. Marie Ládová, who is at the head of an osteological outpatient department in České Budějovice. I stated the serological markers of celiac disease with the assistance of enzymatic immunoanalysis conducted on automatic analyzer Nexgen Four, which was provided by the firm Test-Line. I describe the analyzer, its specification, checking and calibration of the gadget together with determination checks in this part of the thesis. Additionally, there is described the principle of the method ELISA- sandwich, which is non-competitive enzymatic immunoanalysis. At the end of the section there is depicted the methodical procedure of my work, the preparation of working solutions and checks, the preparation and dilution of samples for analysis and working procedure for semiquantitative interpretation with positivity index and for quantitative interpretation U/ml. I continued with my own measurements. while respecting standard operations procedures of the laboratory Stafila, a limited liability company. The results of my measurements are processed in the third part of the thesis. The acquired results are given in a table: quantitative interpretation of the antidote against tTg IgA and IgG (U/ml) level in the sera of the osteoporosis diagnosed patients. Then I presented a graph interpreting the proportional relation of the antidote against tTg IgA and IgG levels in the sera of the osteoporosis diagnosed patients. There are included calibration graphs for tissue transglutaminase IgA and IgG and tables of the obtained data of checks for the methods in the results. 3 out of the 58 examined samples of osteoporotic patients were positive, they had the level of antibodies higher than 22 U/ml. One of the samples had marginal figures, which means it had the antidotes against tTg IgA an IgG between 18 and 22 U/ml. Positive results were found with patients born in 1976 and 1978. A patient born in 1962 appeared to have a marginal result. The acquired antidote figures against tissue transglutaminase in the class IgA and IgG are presented proportionally in the graph 1. 3 out of the 58 measured samples were positive, which represents 5%, and 1 sample was marginal, which is 2%. My analysis is based on the availability of the examined material and the potential of our laboratory. Celiac disease is an illness which was not paid much attention to in the past. Hypothesis about the link between osteoporosis and celiac disease has been proved.
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Zabezpečení laboratorní detekce geneticky modifikovaných organismů
Výzkumný ústav rostlinné výroby‚ Praha-Ruzyně ; Koucká, Petra ; Hodek, Jan ; Pouchová, Vladimíra ; Kučera, Ladislav ; Ovesná, Jaroslava
Podklady pro metodiku vzorkování rostlinných materiálů pro potřeby správních úřadů. Zpracování informací z ENGL pro potřeby ČIŽP. Shromažďování referenčních materiálů. Metodiky stanovení GMO. Svazek obsahuje sborník na téma Geneticky modifikované organismy - současnost, rozšíření a možné interakce s životním prostředím. Jednotlivé příspěvky ve sborníku: geneticky modifikované organismy - základní informace, Možnosti stanovení GMO, Křižitelnost plodin a planých druhů jako potenciál pro únik genetických modifikací, Šíření pylu v porostech lnu setého, Problematika GM hrachu v ČR, Perspektivy využití GMO, Problematika GM bramboru v ČR.
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Zabezpečení laboratorní detekce geneticky modifikovaných organismů včetně mikroorganismů
Vysoká škola chemicko-technologická v Praze, Ústav biochemie a mikrobiologie, Praha ; Zdeňková, Kamila ; Pazlarová, Jarmila ; Demnerová, Kateřina
Spolupráce při přípravě metodik vzorkování a stanovení přítomnosti GMO pro účely kontroly, pokračování spolupráce na přípravě ISO normy vzorkování GMO v rámci skupiny WG 34, účast na práci mezinárodní komise pro akreditaci GMO laboratoří, informace o stavu přípravy příslušných norem na mezinárodní úrovni, zejména v EU, operativní stanovení přítomnosti GMO v rostlinných popřípadě mikrobiálních materiálech ve vzorcích dodaných ČIŽP, rozvíjení mezinárodní spolupráce v rámci ENGL (referenční laboratoř EK pro stanovení GMO), účast na mezinárodních laboratorních porovnáních, prezentované výsledky.
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