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Analysis of nicotin content in some products
Pražáková, Jana ; Kočí, Radka (referee) ; Márová, Ivana (advisor)
This diploma thesis deals with the determination of nicotine in different products. The theoretical part summarizes review on nicotine, smoking and opportunities how to quit. In the practical part a method for the determination of nicotine by HPLC / PDA was optimized. As the most suitable stationary phase was selected a Kinetex 5u C18 100A 150 x 4.6 mm column, as the optimal mobile phase was chosen a pure methanol with a flow rate of 1 ml min-1 and a temperature of 25 °C. For the analysis of nicotine were chosen: 18 kinds of cartridges for electronic cigarettes, two kinds of nicotine gum, nicotine spray, nicotine pastilles, nicotine orodispersible film and ten species of classic cigarettes. For each type of product the most appropriate method for extracting nicotine and its subsequent analysis by HPLC / PDA was found. For tobacco 24 hour extraction in methanol and 10s ultrasound was selected. The nicotine spray and electronic cigarette refills without flavours were only diluted with methanol. Flavoured refills were first diluted by sodium hydroxide and then with methanol. For chewing gums, pastilles and nicotine film extraction with 5% sodium hydroxide was chosen. In this study also new experimental nicotine product was designed. Nicotine has been encapsulated in alginate-starch material to form small gel particles. As the most suitable medium for storage the water medium was determined.
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The measurement of total alkaloids in tobacco
Pipková, Renata ; Vránová, Dana (referee) ; Omelková, Jiřina (advisor)
The aim of this diploma thesis is the assay of total alkaloids in different tobacco types. To measure the content of total alkaloids are utilized types of tobacco used for preparation of tobacco blends and consecutive production of cigarettes. The samples of analyzed tobacco include various countries of cultivation and different crop years. There is described tobacco as a plant, in it contained alkaloids and the utilization of tobacco in the theoretical part. In more detail it deals with the production and construction of cigarettes which is closely related to the content monitoring of total alkaloids in tobacco. The contents of total alkaloids are determined by the continuous flow analyzer- SKALAR. On this spectrophotometer are set the contens of reducing sugars as well. The comparison of total alkaloids contents and reducing sugars from the perspective of single tobacco types, countries of cultivation and crop years is clearly summarized in the experimental part of the thesis that was performed in the company Philip Morris ČR, a.s.
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Smoking in EU Countries
TREFANCOVÁ, Petra
Many cancers, cardiovascular and respiratory diseases are linked to tobacco use. It is the largest avoidable health risk in Europe,causing more problems than alcohol, drugs, high blood pressure, excess weight or high cholesterol. Every year in the EU, as many as 650 000 Europeans die prematurely of tobacco-related causes. It is estimated that, in terms of negative economic impact, smoking costs the EU countries at least ?100 billion. The goal of the thesis is to monitor prevalence of smoking in EU countries. It also deals with efficiency measures for protection against tobacco. The thesis deals with the issue of smoking in historical terms. It also deals in terms of health risks and it describes the measure of EU countries in the fight against smoking. The main part of this thesis is a research, which includes a prevalance of smoking among adults and adolescents, the development of lung cancer mortality and cigarette consumption in each EU country.
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The Problem of Nicotinism at Primary Schools in České Budějovice Region
TVAROHOVÁ, Zdeňka
Abstract More and more young people, also children, are using tobacco products. It is serious patological phenomenon which can effect not only person using the tobacco products, but also the whole society. Using tobacco products causes serious health hazard and diseases, which are usually irreversible. Smoking tobacco is very spread in Czech republic as much as drinking alcohol. Both these phenomenons are tolerated by the society. Society has a big influence on everyone of us and it is very important to prepare healthy environment for curious and inexperienced children. The target of my work is to map the age and motivation factors of the first use of tobacco products, frequency and range of using and attitude towards the smoking. I also target on prevention in schools. Based on the studied materials I stated hypothesis concerning the age of using, realised prevention in schools and ratio between male and female smokers. I used technique of anonymous inquiries. Inquiry was checked by pre-research on which I examined functionality and fullness of the inquiry. Hypothesis {\clqq}I assume that more than half of under age (younger than 15 years) used tobacco products`` was confirmed by the answers in my inquiry. Hypothesis ``I assume that male smokers are more often{\crqq} wasn{\crq}t confirmed. There is 3% more smoking females than males. Hypothesis {\clqq}I assume that realised prevention in school was after the first experience with tobacco and is there for useless`` was also confirmed. It can be presumed of the fact that 17% of the informants didn{\crq}t answer the question, 3% answered ``I don{\crq}t know{\crqq} and 8% answered that they never received any warnings of health riscs in the school. Informants were chosen from two primary schools. Inquiried were total of 203 informants from 6th to 9th grades from ZŠ Kubatova in České Budějovice (91 pupils) and ZŠ Trhové Sviny (112 pupils). Age of the first experience with tobacco products is getting lower, because this inquiry confirmed that average age of the first experience was at 10,9 year of children{\crq}s age. That is why I maintain how important is to prepare complex view of nikotinism problem on primary schools.
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Smoking in nurses
SÝKOROVÁ, Ivana
The aim of the bachelor work to map out the nicotinism occurrence among nurses who have deep knowledge of smoking risk. The research was made by an anonymous questionnaire in the hospitals of the District of Pilsen. It results from the research that the found out prevalence of smoking among nurses (47%) corresponds to the figures stated in the technical literature. The knowledge and awareness of the harmfulness of smoking and the ethic level of nurses proved to be unsatisfactory.
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Prevalence of smoking according to education
JELÍNKOVÁ, Lucie
This dissertation deals with the issue of smoking. Its practical part specifies several objectives, one of them being finding out whether the prevalence of smoking within the population is dependant upon the attained qualifications. Establishing the respondents{\crq} views on the harm of smoking is another goal. The approach of the respondents towards a smoking ban in restaurants is demonstrated in this dissertation, so is their awareness of quitting-smoking methods. The decision to give up is also affected by the knowledge and understanding of all the risks bred by smoking, therefore determining the level of the respondents{\crq} awareness of these health risks is another aim of this dissertation. A quantitative research was used in my dissertation to obtain results. A questionnaire of 18 questions was answered by 211 addressed respondents being in the age group of 45-60 years of age. Analysing the outcome it can be said that the prevalence of smoking within the population is not dependant upon the attained qualifications. Nicotine dependence is referred to as a disease therefore the risk of developing an addiction is the same for everyone irrespective of the qualifications accomplished. Nonetheless, the outcome manifests the fact that smokers with lower qualifications smoke a higher amount of cigarettes a day as opposed to smokers with higher qualifications. Considering the results it can be, furthermore, assumed that smokers with lower qualifications are more tolerant towards the nicotine addiction and they feel less unpleasant in a smoky environment. Moreover, their favour for a smoking ban in restaurants and at working places is lower. At the same time, their awareness of possibilities to treat their nicotine addiction as well as of the negative health effects of smoking proved to be lower. Most smokers would like to quit their nicotine addiction (app. 50% lower- qualified individuals and 72% university and college graduates). However, only a very small percentage would seek any professional help when giving up smoking. The unwillingness to treat the nicotine addiction with the help of an expert reflects the unawareness of the severity of such addiction by the smokers themselves. Therefore, the prevention aimed at non-smokers is as important as effecting smokers so that they become more aware of the seriousness and vast consequences of their addiction.
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Smoking prevalence in students of the Faculty of Health and Social Studies, the University of South Bohemia.
SLAVÍČKOVÁ, Klára
Smoking is becoming a huge problem not only in the Czech Republic but in all developed countries of the world. It is thus worldwide pandemics, which is necessary to take precautions against. Although the smoking prevalence in middle aged men and women is decreasing, it is increasing in both sexes of younger age groups. Especially, the big problem is occasional as well as regular smoking since the age of ten already. This exactly increases the importance of smoking prevalence. Significant role is played by the healthy life style education which should be provided by a family as well as the school educational system. In smokers there is a higher risk of respiratory and cardiovascular diseases; smokers have also higher inclination toward the onset of cancer than non-smokers. The most serious is bronchogenic carcinoma. The thesis was processed by a quantitative way using questionnaires. The research groups were the students of full-time study in the Faculty of Health and Social Studies, the University of South Bohemia. The main objective was to map the occurrence of smoking in students in selected study programmes of the faculty. I stated three hypotheses for the research. Hypothesis 1, students of the faculty are addicted to nicotine and are not satisfied with their addiction, was proved. Hypothesis 2, smokers prevail non-smokers in the group of investigated students, was not proved. Hypothesis 3, students do not lack information on smoking harmfulness, was proved. The research showed that 41.1% women and 40% men suffer from middle addiction to nicotine. The thesis should serve as an information source for the students and lecturers of the faculty and further it might initiate the establishment of the faculty anti-smoking clinic.
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