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Computational modelling of stresses in intracranial aneurysms
Turčanová, Michaela ; Polzer, Stanislav (referee) ; Burša, Jiří (advisor)
The diploma thesis deals with the assessment of the prediction of brain aneurysm rupture based on its geometrical and material properties. In the first part of the thesis there is a~detailed research study of cardiovascular systems with a focus on the cerebral artery and aneurysm occurring on their bifurcates. The second part of the thesis is focused on the creation of two models of arterial cerebral bifurcation with the presence of aneurysm and on obtaining their geometry in unloaded state. Emphasis is placed on the most realistic constitutive model of the artery wall material based on real data from uniaxial tensile tests and on a suitably chosen blood pressure load. This blood pressure may be step-changed, for example, in bungee jumping. In the work, a calculation of the increase in blood pressure during the step-change is performed, which is subsequently used in calculations of tension in the wall of the cerebral aneurysm. In conclusion, the risk of rupture is evaluated in two model idealized brain aneurysms and a discussion of the credibility of the results is given.
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Stress-strain analysis of tumorous total endoprosthesis of hip joint
Vystrk, Tomáš ; Konvalinka, Jan (referee) ; Marcián, Petr (advisor)
Tumorous total endoprosthesis of hip joint is used for reconstruction of the limb affected by bone tumor and to regain its functnion. Longterm load conditions must be considered by the reconstruction and the joint mobility must be enabled. Suitability of the endoprosthesis depends on its construction considering shape, material and with this related mechanical properties. This thesis deals with creation of computational model and stress-strain analysis of tumorous total endoprosthesis of hip joint. There are two different types of endoprosthesis modeled in this thesis, each with three different length of resected bone replacement. Based on stress-strain analysis an assessment of possible limit states is made.
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Biomechanical Studies of Facial Bone
Valášek, Jiří ; Janíček, Přemysl (referee) ; Horyl, Petr (referee) ; Florian, Zdeněk (advisor)
Presented work deals with Biomechanical study of the facial skeleton. This work is focused on the fixation of the mandible after removal of a tumor from affected bone tissue. The aim of the work is to perform biomechanical study of the facial skeleton with subsequent detailed stress strain analysis of two mandible implants designed and manufactured for specific patients. The geometry model of mandible used for design of mandible implants and used for computational modelling has been obtained on the basis of CT data of two patients. A Theoretical-Clinical sub-study that deals with the comparison the CT data processing which is necessary for creating the model of geometry is a part of the thesis. Two models of mandible with applied mandible implant have been created for two specific patients with tumorous mandible bone tissue. Stress strain analysis has been performed for these two models. Results of the stress strain analysis of two models of mandibles with mandible implants are presented in the final chapters of the thesis. Findings of the biomechanical study have been published and applied in clinical practice.
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Application of tensegrity structures in modelling of mechanical behaviour of smooth muscle cells
Bauer, David ; Fuis, Vladimír (referee) ; Burša, Jiří (advisor)
The master’s thesis deals with the computational modelling of the mechanical testing of isolated smooth muscle cells. The main aims are to create computational model of a cell, to simulate single-axis tensile test and to modify the model so that the model reflects real mechanical response. The model of the cell includes cytoplasm, nucleus, cell membrane and cytoskeleton which is modelled as a tensegrite structure. On this model the tensile test was simulated in case of the cell with cytoskeleton and the cell with distributed the cytoskeleton. Force-elongation curves, which were obtained from this simulation, were compared with experimental data which were taken from literature. Tensile properties were measured on freshly isolated cells from rat thoracic aorta, cultured cells, and cells treated with cytochalasin D to disrupt their actin filaments. It was found that the cytoskeleton influence on the cell load in computational model was smaller than in the real cell. Therefore the model was modified by changing material propreties and geometry so that the model of the cell corresponded with the different types of experimentally measured cells.
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Strain-stress analysis of fixed bone of foot
Zapletal, Jakub ; Fuis, Vladimír (referee) ; Návrat, Tomáš (advisor)
This diploma thesis deals with analysis of the rigidity of different variations of foot fixations. In the thesis there is a description of elementary anatomy of foot and its patology. Furthermore the possible corrections of hallux deformities and chosen fixators are described. The problem of analysis is soluted by the method of finite elements. The thesis also includes steps of geometery model creation based on 3D scanning. Three differents types of fixations are compared in this thesis and each of them is created in two different levels of details. There is a comparation, analysis of final solutions and chosen influences on the rigidity in the conclusion.
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Biomechanical Study of Cranial Implants
Chamrad, Jakub ; Henyš,, Petr (referee) ; Fuis, Vladimír (referee) ; Florian, Zdeněk (advisor)
Tato práce s názvem Biomechanická studie lebečních implantátů se zabývá především výpočtovým modelováním jak nepoškozené lebky, tak i lebky s defektem a lebečním implantátem. Přístup řešení pro vyhodnocování deformačně-napěťových stavů systému lebka-implantát-fixační prvky byl prováděn pomocí výpočtového modelování metodou konečných prvků. Pro validní analýzy a interpretaci výsledků je třeba zvolit vhodnou úroveň výpočtových modelů. Výběr úrovně výpočtového modelu je z tohoto důvodu zásadním problémem, kterému jsou věnována značná část této práce. Bylo prokázáno, že volba úrovně má přímý vliv na hodnoty zkoumaných biomechanicky významných parametrů. Dalším faktorem, který ovlivňuje chování lebečního implantátu a jeho funkčnost, je rozměrová přesnost vyrobené kostní náhrady. Bylo pozorováno, že i malá rozměrová odchylka může způsobit změnu deformačně-napěťových stavů na lebce se zavedeným implantátem a způsobit tak rizikovou situaci z pohledu selhání implantátu nebo jeho fixace. Především způsob fixace implantátu bývá rizikový a snižuje spolehlivost implantátu. Je proto vhodné se na tuto oblast zaměřit a navrhnout možné způsoby zlepšení stávajících postupů nebo navrhnout nové způsoby fixace. Jedním ze zlepšení metody fixace implantátu k lebce může být použití hydroxyapatitového potahu na kontaktním rozhraní kost-implantát. To by mělo vést k oseointegraci, což je požadovaný efekt, který byl v této práci výpočtově modelován a vyhodnocován.
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Optimization of nozzles for firefighter sport
Páral, Filip ; Klas, Roman (referee) ; Fialová, Simona (advisor)
This thesis deals with flow inside of the firesport nozzles. Those are used for a fire attack, one of the firesport disciplines. The research part of this thesis introduces a fire attack, commonly used equipment and hydraulic losses that occur during the flow. This part also consists of an overview of current firefighting and firesport nozzles. It includes requirements for nozzles that are used in the fire attack discipline. Second part of the thesis presents the flow analysis inside firesport nozzles using commercial software for computational fluid dynamics (CFD), ANSYS Fluent. Several nozzle designs are proposed at the end of this thesis, based on conclusions from previous part. These designs satisfy firesport nozzle requirements, previously stated in this thesis.
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Stress analysis of the total hip joint endoprosthesis head under ISO 7206-5 loading
Varga, Jozef ; Hlavoň, Pavel (referee) ; Fuis, Vladimír (advisor)
The aim of this work is to analyse axisymetric tasks by norm ISO 7206-5, which is used to determination of static strength of ceramic heads. In the numeric analysis there will be considered form variances from nominal conicalness and circularity of stem sections i.e. possible variances caused by production. Furthermore form changes of recess inside of the head measured on real samples will be considered. All these variances from nominal values are necessary to analyse in more details, because they can participate in destruction of ceramic heads. The stem system, ceramic head and load cone (DHK) will be simulated as a 2D axisymetric task and 3D quarter symetrical task. That is why is necessary to undertake also comparing analysis of 2D and 3D tasks and compare results or eventually evaluate the error. This problem is solved using of Finite element System ANSYS 11.0.
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