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	Evaluation of numerical representations suitability for overlap detection Pleskačová, Barbora ; Maděránková, Denisa (referee) ; Jugas, Robin (advisor) The bachelor´s thesis is focused on the evaluation of numerical representations suitability for overlap detection. Introductory part deals with description of deoxyribonucleic acid structure. The next part discribes sequencing methods and genome assembly techniques. Following part deals with numerical representations that convert DNA sequences into numerical form. Based on similarity metrics, the use of these representations is tested for the detection of overlaps between DNA reads. In the practical part of the thesis an algorithm for overlap detection is designed and implemented using numerical representations. The algorithm is then tested on data. Detailed record
	De novo genome assembly of Arthrobacter sp. isolated from arctic permafrost soil ŠATROVÁ, Mariana A draft genome was assembled from newly sequenced Arthrobacter species isolated from arctic soil. The raw sequences were analyzed and their statistics discussed in great depth. Several assemblers were tested and compared for results. The best assembly (the final draft genome) was then uploaded to RAST server and annotated. Detailed record
	Signal processing based methods for genome assembly refinement Jugas, Robin ; Provazník, Ivo (referee) ; Sedlář, Karel (advisor) The diploma thesis deals with sequencing methods and genome assembly methods including usage of numerical representations. The theoretical part of thesis describes the history of DNA research, generations of sequencing methods, the assembly methods themselves and definiton of numerical representations. Numerical represenatations serve to convert character form of DNA to numerical form and so allow to use digital signal processing methods. There is an algorithm for genome assembly using numerical represenatation proposed in thesis, which is later tested at sequence data. Detailed record

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