National Repository of Grey Literature 12 records found  previous11 - 12  jump to record: Search took 0.02 seconds. 
Determination of drug residuals using separation methods
Vašíčková, Petra ; Opatřilová, Radka (referee) ; Vávrová, Milada (advisor)
Nonsteroidal anti-inflammatory substances became a very frequently used and constantly evolved group of the drugs, particularly in a human medicine. The risk of their penetration into the environment, especially to the water environment, is rising during the recent years. The diploma thesis is focused on a selection of appropriate separation method and optimization of analytical procedure for the identification and determination of the non-steroidal anti-inflammatory drugs in sewage and surface waters. Salicylic acid, ketoprofen, diclofenac and ibuprofen were chosen from the wide range of NSAIDs as the most widespread agents of this drugs group in the medical practice. The method was optimized and elaborated using the model water samples. This method was used for determination of the analytes contained in the real water samples. Waste water samples were taken from the large-scale wastewater treatment plant in Brno-Modřice and surface water samples were taken from the Highlands river Křetínka. Solid phase extraction (SPE) was used for the real samples treatment and preconcentration, the determination was performed using the high performance liquid chromatography with mass spectroscopy method (LC-MS).
Assessment of drugs in settlings with waste water treatment
Hájek, Radek ; Mravcová, Ludmila (referee) ; Vávrová, Milada (advisor)
This bachelor thesis is focused on asessment of pharmaceuticals in wastewater treatment plant sludge. Two macrolide antibiotics (erythromycin and clarithromycin) and three non-steroidal anti-inflammatory drugs (ibuprofen, naproxen and diclofenac) were assessed. Sample of sludge was taken in municipal wastewater treatment plant in Brno-Modřice. Analytes were obtained using pressurized solvent extraction (PSE) or ultrasonic solvent extraction (USE). Clean-up was performed by solid phase extraction (SPE). Ultra high performance liquid chromatography followed by UV-VIS diode array detection was used for quantitative determination of the analytes.

National Repository of Grey Literature : 12 records found   previous11 - 12  jump to record:
Interested in being notified about new results for this query?
Subscribe to the RSS feed.