National Repository of Grey Literature 2 records found  Search took 0.00 seconds. 
Dramatically Higher Sensitization to Outdoor Plant Allergens in Czech than in Ukrainian Atopic Patients
Gusareva, Elena ; Havelková, Helena ; Belozorov, A. P. ; Blažková, Hana ; Savvo, A. ; Lipoldová, Marie
Inherited predisposition to hyperproduction of IgE against common environmental allergens. It is a major risk factor for clinical expression of allergic diseases.The prevalence of atopic disorders is rising worldwide, but the reason for this is unknown. Moreover, the allergens triggering and supporting the development of atopy vary in different areas. The reason for this most likely includes diversity of allergens prevalence in different environment. Therefore, determination of major allergens is important when performing diagnostic testing and selecting immunotherapy. It also could provide important clues to the etiology of atopic disorders in a certain geographical area.
Interaction of sperm surface proteins in the reproduction process
Jonáková, Věra ; Kraus, Marek ; Maňásková, Pavla ; Liberda, J. ; Tichá, M.
Mammalian fertilization includes highly regulated biochemical interactions between complementary molecules located on the surfaces of both gametes as well as those present in the natural environment of the gametes. Boar seminal plasma proteins AQN, AWN spermadhesins and DQH protein that are bound to the sperm at ejaculation play important role in the reproduction process. Binding of sperm to epithelial cells, recognition of gametes and binding of sperm to glycoprotein of zona pellucida are mediated by protein-saccharide interaction, lektin-type interaction. Another type of interaction (protein-protein) participates in the formation of aggregated forms, which seem to be the natural functional forms of seminal plasma proteins. Protein aggregates form the sperm coating layers and their re-modeling in the female reproductive tract is imporatnt for the sperm capacitation and for the primary binding of spermto the ovum.

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