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National Repository of Grey Literature 2 records found  Search took 0.01 seconds. 
Human health risks of cyanobacterial toxins /Microcystins/ in Brno Reservoir
 Maršálek, Blahoslav ; Babica, P. ; Bláha, Luděk
Monitoring of cyanobacterial blooms showed, that significant health risks of both direct dermal contact as well as exposure to microcystins exist in recreation in Brno. During the summer season 2001, safety limits for dermal contact were exceeded at 93% of analysed localities. Our results iniciate that both monitoring and regelatory actions ase necessary.
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Screening of the health risks of biofilms using a battery of in vitro toxicity assays
 Bláha, Luděk ; Babica, P. ; Sabatier, S. ; Admiraal, W. ; Maršálek, Blahoslav
Traces of microcystin-lika compounds were detected by HPCL in biofilm samples from Netherlands. Half of the tested samples had no significant effect in any of the in vitro assays, other biofilms elicicted weak inhibitory/toxic effects mostly in high concentrations, which are not environmentally relevant. Most of observed weak effect seem to be associated with oxidative stress, an important toxicologicalĺmechanisms, as detected by depletion of intracellular antioxidantĺGHS by several biofilm samples. Potential adverse effects ofĺexterne polutants, which are known to accumulate in theĺperyphyton biomass should not underestimated. Mutagenicity andĺneurotoxicity of biofilm metabolits seems to be negligible. Weekĺadverse effects of biofilm extracts detected in a batery of inĺvitro assays indicate relatively low human health risksĺassociated with biofilm toxicity.
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