|
| |
|
| |
|
|
Quantitative modelling of effect of transverse-axial tubular system on electrical activity of cardiac cells under low [K+]e
Pásek, Michal ; Christé, G. ; Šimurda, J.
In this work, we explored quantitatively the effect of ion concentration changes in the restricted space of transverse-axial tubular system (TAT-system) on ventricular cell arrhythmogenesis under the conditions of low extracellular potassium concentration ([K+]e). The simulations were performed on a model that integrates the quantitative description of electrical activity of surface and tubular membrane with the quantitative description of dynamic changes of intracellular ion concentrations. The results predict that the TAT-system plays a significant protecting role in cellular arrhythmogenesis that arises from the enhancement of potassium concentration gradient between tubular and extracellular spaces at low level of [K+]e.
|
|
| |
|
| |
|
|
Scatter plot and confidence interval
Halámek, Josef ; Holík, M. ; Jurák, Pavel
The exact definitions and standardisation are mostly missing in the area of biosignal measurement and processing. That in why the choice of the optimal method must be based on multidimensional statistical analysis. In this case the scatter plot with confidence ellipses can be used successfully.This graphical method is very simple and comprehensive. According to analysed parameters the method is two-dimensional, according to analysed groups multidimensional.
|
|
|
Baroreflex sensitivity and heart rate
Halámek, Josef ; Jurák, Pavel ; Swenne, C. A. ; Kára, T. ; Souček, M. ; Eisenberg, M. ; Nykodým, J.
The correlation between baroreflex sensitivity (BRS) and heart rate (HR) is discussed. According to theoretical model, where the constant blood flow is supposed, the BRS given in [ms/mmHg] must correlate with HR and BRS in [mHz/mmHg] should not correlate with HR. This assumption was confirmed by the measurement on healthy young subjects, but it is not valid for old healthy subjects and for patients.
|
host ::
RSS.