Národní úložiště šedé literatury Nalezeno 3 záznamů.  Hledání trvalo 0.00 vteřin. 
Phylogeny of human populations in Papua New Guinea, a genetic and linguistic diversity hotspot
KOPICOVÁ, Klára
A detailed phylogeny of human populations in Papua New Guinea was constructed using exhaustive topology exploration, and the fit of the model to the data was improved by adding several admixture events. The analysis relied on published genome-wide SNP genotyping data for hundreds of individuals, and qpGraph was a principal method employed in the study for testing the fit of admixture graphs to the data.
Traditional plant breeding,advanced biotechnological engineering with emphasis on GM crops and environmental risk assessment of GMs
KOPICOVÁ, Klára
While searching for the best approach that would ensure an adequate supplement of the current still growing world population, the national governments support different strategies to multiply crop production and to stabilize profits. It is obvious that traditional plant breeding techniques are not capable to meet this challenge. Hence, scientists developed an advanced plant breeding techniques that cope with the adversity of the environment (e. g. pest and weed pressure, drought, salinity) as well as satisfy major needs of human society (e. g. sufficient yields, nutrient content). However, advanced bioengineering arouses distrust in consumers. This review compares both, the advanced plant breeding techniques with traditional breeding approaches; and the debate is further extended by critical assessment. Further focusing on genetic modifications (GMs) and genetically modified (GM) crops, this study describes a status of their growing on the example of two completely different strategies - strategy of the United States (U.S.) and the European Union (EU). Additionally, this thesis suggests a new design for testing of GM crops environmental risk assessment (ERA) - more precisely, a very little explored, potential transfer of GM gene constructs into invertebrates.
The role of adenosine receptor in self-activation in immune cells
KOPICOVÁ, Klára
Adenosine receptor plays very important role in regulation of immune response. Its signalling may lead to initiation of metabolic switch, which suppresses energy consumption by peripheral tissues (selfish behaviour of immunes system). In this thesis I attempt to test the potential role of adenosine signalling in self-activation of immune cells which could alternatively explain its role in systemic energetic switch in model organism Drosophila melanogaster.

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