Národní úložiště šedé literatury Nalezeno 2 záznamů.  Hledání trvalo 0.00 vteřin. 
Late Steps in the cytosolic Iron-Sulfur Cluster Assembly in Trypanosoma brucei
HAINDRICH, Alexander Christoph
The aim of this thesis was to investigate genes involved in the late steps of the Cytosolic Iron sulfur cluster Assembly (CIA) pathway in procyclic T. brucei, to determine their cellular localization and find their possible interaction partners and substrates.
Iron-Sulfur Cluster Assembly in Trypanosoma brucei
HAINDRICH, Alexander Christoph
In this thesis we investigated genes of the Cytosolic Iron sulfur cluster assembly (CIA) pathway in T. brucei procyclic and blood-stream form for their possible functional redundancy. For this, RNAi double knockdown plasmids were generated containing knockdown partners which were selected based on the proposed model of the CIA pathway in S. cerevisiae. The generated plasmids were transfected into T. brucei cells, and growth effects on the transfectants upon tetracycline induced RNAi was measured.

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