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In vitro antioxidative effect of medicinal plants from Ghana
Addai, Benjamin Berkoh ; Kokoška, Ladislav (vedoucí práce) ; Tauchen, Jan (oponent)
The in vitro antioxidative activity of crude extracts derived from sixteen Ghanaian plant species (Allophylus spicatus, Cnestis ferruginea, Ficus thonningii, Indigofera hirsuta, Indigofera pulchra, Launaea taraxacifolia, Leea guineense, Mikaniopsis tedliei, Millettia thonningii, Philenoptera cyanescens, Salacia senegalensis, Senna occidentalis, Stachytarpheta indica, Tiliacora warneckei, Triumfetta rhomboidea, Vernonia colorata) were tested in frame of this study using 1,1-diphenyl-2-picrylhydrazyl radical scavenging capacity assay. The extract from the bark of Indigofera hirsuta has been found as the most active sample (IC50 = 12.84 more or less 0.82 microgram per millitres), because its activity is very close to the positive control Trolox and ascorbic acid. We expect that this finding may be used by pharmaceutical industry for development of new herbal-based nutraceuticals and pharmaceutical preparations.
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