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National Repository of Grey Literature

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Drug utilization of specific biotherapeutic agents and biosimilars in the Czech Republic Vasko, Olha ; Dvořáčková, Simona (advisor) ; Babica, Jan (referee) Drug utilization of specific biotherapeutic agents and biosimilars in the Czech Republic Author: Olha Vasko Supervisor: PharmDr. Simona Dvořáčková, Ph.D. Department of Social and Clinical Pharmacy Faculty of Pharmacy in Hradec Králové, Charles University in Prague Introduction: Biosimilars represent an alternative to innovative biological medicinal products, contribute to improvement of the effectiveness of treatment and enable to gain access to expensive therapy of serious diseases. Objective: The objective of the practical part of the diploma thesis was to analyze trends in drug utilization of specific biotherapeutic agents and biosimilars in the Czech Republic between 2008-2022. The secondary aim of the practical part was analysis of the expenditures for specific biotherapeutic agents and biosimilars in given period. Methods: Drug utilization from the database of the State Institute for Drug Control has been evaluated from 2008 until 2022. The values of defined daily doses were used to process the results, which were subsequently converted to the number of defined daily doses per 1000 inhabitants per day (DID). Descriptive statistics was used for the retrospective analysis of the drug utilization. The following drugs were included in the analysis: filgrastim, pegfilgrastim, lipegfilgrastim,... Detailed record

See also: similar author names
10	Vasko, Ondrej
2	Vaško, Oskar
10	Váško, Ondřej

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