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Automated Measurement of Ultrasound Markers of Congenital Fetal Abnormalities
Szpyrc, Bogdan ; Kolář, Radim (referee) ; Provazník, Ivo (advisor)
This work deals with displaying and measuring ultrasonic markers of congenital defects of the fetus in first trimester of pregnancy. Background research of ultrasonic markers was based on the studies of prof. Kypros Nicolaides (Great Britain), the president of the Fetal Medicine Foundation. This work contains a brief description of diagnosing of congenital defects during all three trimesters, and lists in detail defects that can be diagnosed properly during first trimester, as well as methods of calculating the risk of chromosomal abnormalities. In the next parts of this work, there are descriptions of methods used to improve results while measuring nuchal translucence (NT) strongest marker of Down syndrome in first trimester. The imaging capabilities of ultrasound devices were tested. Using scanned images, the influence of different display parameters on the resolution could be determined. Furthermore, using recommendations of the FMF, algorithms for adjusting correct slice of fetus and automatic measurement NT were designed and tested. A program application was designed that enabled testing of those algorithms on real images and calculating risks of chromosomal abnormalities from CRL and NT value. Designed algorithms were tested on real images. The program application, in witch the algorithms for measuring NT (NT detection algorithms) are included, was created.
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Measurement of cardiovascular parameters
Szpyrc, Bogdan ; Rychtárik, Milan (referee) ; Kolářová, Jana (advisor)
This bachelor thesis deals with the questions of anatomy and physiology of the heart. The diagnostic system BIOPAC is used in order to measure the electrical activity of the heart by a 12-lead electrocardiogram (ECG) and to evaluate the heart rate. The ECG signal is transformed into a vectorcardiogram (VCG) from which the direction of the electrical axis of the heart is deducted. Own experiment will be suggested in order to detect a load reaction and cessation of breath on the heart rate and a load reaction on an inclination of the electrical axis of the heart. A programme application will be designed so as to simplify the analysis of values. The application will allow reconstruction of the ECG signal into a VCG scheme and an automatic calculation of the heart rate and the inclination of the electrical axis of the heart. By means of a statistical analysis the results of measurements will be evaluated.
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Automated Measurement of Ultrasound Markers of Congenital Fetal Abnormalities
Szpyrc, Bogdan ; Kolář, Radim (referee) ; Provazník, Ivo (advisor)
This work deals with displaying and measuring ultrasonic markers of congenital defects of the fetus in first trimester of pregnancy. Background research of ultrasonic markers was based on the studies of prof. Kypros Nicolaides (Great Britain), the president of the Fetal Medicine Foundation. This work contains a brief description of diagnosing of congenital defects during all three trimesters, and lists in detail defects that can be diagnosed properly during first trimester, as well as methods of calculating the risk of chromosomal abnormalities. In the next parts of this work, there are descriptions of methods used to improve results while measuring nuchal translucence (NT) strongest marker of Down syndrome in first trimester. The imaging capabilities of ultrasound devices were tested. Using scanned images, the influence of different display parameters on the resolution could be determined. Furthermore, using recommendations of the FMF, algorithms for adjusting correct slice of fetus and automatic measurement NT were designed and tested. A program application was designed that enabled testing of those algorithms on real images and calculating risks of chromosomal abnormalities from CRL and NT value. Designed algorithms were tested on real images. The program application, in witch the algorithms for measuring NT (NT detection algorithms) are included, was created.
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Measurement of cardiovascular parameters
Szpyrc, Bogdan ; Rychtárik, Milan (referee) ; Kolářová, Jana (advisor)
This bachelor thesis deals with the questions of anatomy and physiology of the heart. The diagnostic system BIOPAC is used in order to measure the electrical activity of the heart by a 12-lead electrocardiogram (ECG) and to evaluate the heart rate. The ECG signal is transformed into a vectorcardiogram (VCG) from which the direction of the electrical axis of the heart is deducted. Own experiment will be suggested in order to detect a load reaction and cessation of breath on the heart rate and a load reaction on an inclination of the electrical axis of the heart. A programme application will be designed so as to simplify the analysis of values. The application will allow reconstruction of the ECG signal into a VCG scheme and an automatic calculation of the heart rate and the inclination of the electrical axis of the heart. By means of a statistical analysis the results of measurements will be evaluated.
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