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Synchronizace říje plemenic skotu a její úspěšnost
SUKOVÁ, Denisa
Reproduction and milk production are considered to be the main factors influencing the whole economy of cattle breeding. We have been monitoring the worsening reproduction related to cattle breeding for a long time. The introduction of synchronization protocols into reproductive management is a posibility to improve reproduction. The aim of my work was to detect the success rate of insemination after rut synchronization on the basis of the data analysis and to evaluate reproductive indicators. The monitoring was performed from January 2017 to June 2018. There were monitored 310 breeding Holstein cows with the yield level of 10 335 kg of milk. The data were obtained from the zootechnical records and the Farmsoft Program. The breeding reproductive level was poor. Here are following values of reproductive indicators: insemination interval - 63 days, service period - 124 days, intervening time - 407 days, intersemination interval - 35 days, insemination index - 2,63 and pregnancy after the first insemination - 33,23%. That was only the insemination interval to achieve great results because breeding cows were involved into the synchronization protocol Presynch within 31 to 38 days after birth. It was detected that cows after the synchornization program Presynch got pregnant in 36,6% after the first insemination, whereas breeding cows being inseminated for the required rut became pregnant in 28% cases after the first insemination. The percentage of pregnancy in synchronizated cows after the first insemination is almost identical to the average in the Czech Republic (37,1%). Performing hormonal therapy within Presynch increased the reproductive costs in one cow by 211 Czech crowns.
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Studium vlivu mykotoxinů ve výživě zvířat
SUKOVÁ, Denisa
This bachelor thesis deals with mycotoxins, their impact on health and productivity of farm animals. Mycotoxins are toxic secondary metabolites of fungi. The introductory part of the thesis focuses on the basic fungi and mycotoxin characteristics. Further, the classification of mycotoxins is described. A significant part of this thesis is made of the characteristics of individual mycotoxins and their impact on health and productivity of farm animals. Great emphasis is put on the prevention of formation and decontamination of mycotoxins in animal food. The conclusion mentions legislation as well as limits
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Knowledge of pupils of upper primary schools in the field of protection of population in South Bohemian region
SUKOVÁ, Denisa
Lives of each of us may bring unexpected situations, such as natural disasters, accidents involving release of hazardous substances or extensive traffic accidents. Statutory regulations and organizational measures taken by the state serve to mitigate the consequences of such emergencies. One of the tasks of the state is to protect the society, which also involves protection of population. Citizens themselves can contribute to the mitigation of the consequences of emergencies. Therefore, it is important to educate the citizens in this regard for them to be able react adequately. As part of the training of the population it is important to inculcate children from their early age with the basic rules of protection and help. Thus the issues of protecting people in emergencies are part of framework educational programmes for preschool, elementary as well as secondary education. It is the issues of protection of population that the theoretical part of this thesis deals with. The introduction describes protection of population from a historical perspective. It subsequently describes the current situation not only in the Czech Republic but it also briefly describes the context of the European Union and the political-military organization NATO. The thesis also describes the system of education in the sphere of protection of population at elementary schools. An integral component of the theoretical part is a chapter dealing with the integrated rescue system. The theoretical part is concluded with a chapter on statistical methods. The objective of the thesis was to find out about the level of knowledge of pupils in the 6th and 9th grades in the sphere of protection of population at selected schools in the South Bohemia region and to compare, subsequently, the knowledge of these pupils using the methods of descriptive and mathematical statistics. The following hypothesis was formulated for this thesis: 'Pupils on the 9th grade of elementary schools in the South Bohemia region have significantly better knowledge in the sphere of protection of population than 6th-grade pupils.' To achieve the defined objectives and to test the hypothesis, it was necessary to create a questionnaire focusing on the issue and to carry out a survey. The research group consisted of 100 pupils from 6th-grade classes and 100 pupils from 9th-grade classes at eight elementary schools in the South Bohemia region. The questionnaire submitted to the pupils included 15 questions. The questions in which the pupils showed a lack of knowledge mainly included questions focused on first aid. Evaluation of the questions shows that only 25 % of the pupils surveyed know what the frequency of chest compressions during resuscitation of an adult is and that 54 % of the pupils know how to behave in a situation where somebody is a victim of a high-voltage electric shock. Another problem area is the knowledge of signals. Only 51 % of the respondents know the signal for 'General Warning' and know what to do in the event this signal is sounded. The signal of 'Acoustic Siren Test' is known by only 21 % of them. In contrast, the issues in which pupils showed a good knowledge include, for instance, emergency telephone numbers (85 % of correct answers), integrated rescue system (87 % of correct answers) or evacuation (86 % of correct answers). Overall, the 6th-grade pupils answered all the questions correctly in 52.9 % of cases; it was 58 % in the 9th-grade pupils. The selected hypothesis was tested and confirmed using the methods of descriptive and mathematical statistics. The processed data is presented in the 'Results' chapter and it is subsequently evaluated in the 'Discussion' chapter. The benefit of this thesis is in an obtained image of knowledge in the sphere of protection of population shown by pupils of elementary schools. The outputs of the thesis have been provided to the participating schools.
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Secondary tumors after irradiation for carcinoma of the breast
SUKOVÁ, Denisa
One of the most common cancers in women is breast cancer. The incidence of breast cancer is great and its incidence increases after 50 years of age. In 2009, 5,975 women were newly diagnosed. Despite the fact that the treatment of breast cancer, especially in its early stages, is very successful, breast cancer still remains the leading cause of cancer death in women. In 2009, 1,607 women succumbed to this pestilential disease. The main treatment modality is surgical treatment. Breast cancer is moderately chemosensitive and radiosensitive, which suggests a potential treatment using chemotherapy and radiotherapy. Other treatment modalities include hormonal and biological therapies. Radiotherapy is a medical discipline that uses ionizing radiation to treat malignant as well as benign diseases. When applying ionizing radiation, tolerance doses of organs and tissues must be observed. As a result of exceeding the tolerance doses, significant changes and complications reducing the quality of life arise. Because the survival rate of cancer patients is increasing, the study of late effects of cancer treatment is becoming more important. One of the serious late side effects is the formation of secondary tumour. The practical part of the thesis focuses on the issues of radiation-induced tumours in women who have been treated with radiotherapy for breast cancer. The research group consists of patients who were exposed to radiation at a hospital in České Budějovice between 2000 and 2004. The entire group included 516 patients who were exposed to radiation aimed to the breast or chest wall. I monitored in these patients the eventual formation of a duplicate tumour, its location, type, and latency time. I also focused on the calculation of relative risk. After the completion of radiation therapy, a secondary tumour formed in 32 patients, i.e. 6.2 %. Two new tumours were found in one of the patients, the total of 33 secondary tumours was diagnosed. The most frequent types of newly formed tumours were cancers of contralateral breast and non-melanoma skin cancers (basal cell epithelioma). Both tumour types were represented in the number of seven. Furthermore, six lung tumours, three rectal tumours, and two cases of cervical, kidney and bladder tumours were found. In addition, a duplicate tumour of the brain and the meninx, a myeloma, a thyroid tumour, and an endometrial tumour were found. 58 % cases of duplicate tumours were located outside the irradiated areas. Four of the six newly formed lung tumours, three of the seven newly formed skin tumours, and seven tumours in the contralateral breast were identified in the irradiated areas. Latency time till the formation of duplicate tumours ranged from two to twelve years. The median of the latency time was seven years. Within five years after irradiation a total of 14 secondary tumours formed, i.e. 42 % of the total. Within ten years after irradiation most of the duplicate tumours formed. 17 duplicates were diagnosed in this category, i.e. 52 %. 52 %. In one type of cancer (3 %), brain tumour, and meninges, the latency time was 12 years. Furthermore, I calculated relative risk. The values of relative risk determined were greater than 1 for all types of tumours. The lowest value relative risk was observed in skin cancer, which was 1,939. On the other hand, the highest value of the relative risk was observed in endometrial neoplasm. The value of relative risk reached 48.78. Through this calculation of relative risks I confirmed the hypothesis that after irradiation of breast cancer there is an increasing number of duplicate tumours in comparison with the occurrence of tumours in the general population. Despite the increased values of relative risk, the benefits of radiotherapy in cancer treatment are irreplaceable. When using radio therapy, it is necessary to count with some risk of late complications.
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Usage of retraining the Bureau of Labor to increase the applicability of the labor market
SUKOVÁ, Denisa
The graduation essay deals with the use of requalification courses in employment bureaus; such courses rank among tools increasing the chances of job applicants to assert themselves in the labour market. The introductory section of the essay focuses on the theoretical definition of this issue, including related topics. The first main purpose of the research was to map out the opinions of job applicants registered with the employment bureau in Strakonice regarding the situation of re-qualified people in the labour market. Quantitative investigation, the inquiry method, the questionnaire technique was employed to test hypotheses and to collect primary data. Two hypotheses were determined for the research: Hypothesis 1: Attendants of requalification courses consider requalification less efficient than applicants who have not taken advantage of this service yet. Hypothesis 2: Job applicants find non-specific requalification more accessible than specific requalification. Research results showed that hypothesis 2 was confirmed, while hypothesis 1 was not confirmed. The second main purpose of the work was to map out opinions of consultants in labour bureaus regarding the utilization of requalification courses. The research was complemented with qualitative investigation in which the inquiry method, the semi-controlled interview technique was applied. Interviews were conducted with professionals from employment bureaus that deal with requalification. The purpose of the interviews was to find out how requalification is implemented and what those professionals think of its importance. Interviews were conducted face to face. The following conclusion was made based on the qualitative inquiry: Consultants in the employment bureau appreciate requalification not only because re-qualified people gain new knowledge and skills, but also because such courses enhance their self-esteem which is so important in the process of searching for a job.
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