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Analysis of vaccine utilization and spontaneous adverse events reports in influenza vaccine
Podskalská, Markéta ; Zimčíková, Eva (advisor) ; Kolmanová, Eliška (referee)
Analysis of vaccine utilization and spontaneous adverse events reports in influenza vaccine Author: Markéta Podskalská Supervisor: PharmDr. Eva Zimčíková, Ph.D. Department of Social and Clinical Pharmacy, Faculty of Pharmacy in Hradec Králové, Charles University Introduction and goal: Influenza is a contagious disease of the respiratory system. It is caused by influenza viruses and appears in annual outbreaks. The best form of influenza prevention is vaccination against influenza viruses on yearly basis. The vaccination has many benefits, but some side effects may appear as well. Goal of this thesis was to analyse and evaluate reports of side effects of influenza vaccination between years 2004-2017 and to evaluate the use of influenza vaccines from 2004 to 2022. Methodology: The Central Database of Adverse Events Reporting of the State Institute for Drug Control was used as the data source. Reports with the ATC code J07BB in the period from 2004 to 2017 were evaluated. Information about the patient, reporting person, the region where the notification was filed, the method of reporting and details concerning adverse events were analysed. These details included the number and severity of adverse effects, their predictability and final outcome. Data on influenza vaccine usage were provided by SÚKL....
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