Home > Search Results: Mertová, Ivana
Search:
Search Tips :: Advanced Search
Search collections:
Sort by: Display results: Output format:
National Repository of Grey Literature 1 records found  Search took 0.00 seconds. 
Effect of ivermectin on the adults of Haemonchus contortus
 Mertová, Ivana ; Matoušková, Petra (advisor) ; Vokřál, Ivan (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Biochemical Sciences Candidate: Ivana Mertová Supervisor: Ing. Petra Matoušková, Ph.D. Title of diploma thesis: Effect of ivermectin on the adults of Haemonchus contortus Helminthiasis is a disease caused by helminth parasites including barber's pole worm (Haemonchus contortus - H. contortus) that causes haemonchosis. Haemonchosis is a serious disease harming small ruminant breeding and causing loss of productivity of animals, breeding weakening and ultimately death of the animals. Anthelmintics are widely used in struggle against the disease but frequent use in the past and present has led to developing drug resistance of the parasites. Increasing resistance against compounds with anthelmintic activity is becoming a worldwide problem. The effort is to know the resistance mechanisms and contributing factors which would prevent formation and expansion of the resistance. One of the most widely used substances of veterinary therapy of helminthiasis remains ivermectin (IVE). It is a macrocyclic lactone whose mechanism of action is likely damaging the parasite's chloride channels of glutaminergic synapses. This project studies the effect of IVE on adults of two strains of H. contortus: the sensitive strain, called ISE...
Detailed record

See also: similar author names
2 Mertová, Irem
1 Mertová, Iva
Interested in being notified about new results for this query?
Subscribe to the RSS feed.
Digital Repository :: Search :: Submit :: Personalize :: Help
Powered by Invenio v1.1.2
Maintained by admin.invenio@techlib.cz
This site is also available in the following languages:
Česky  English