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Hereditary breast cancer
Malegová, Jana ; Bendová, Marie (advisor)
Malignant tumors of the breast are the most common malignant disease in women Czech Republic and in the world and one of the most frequent causes of their death , because this is a very important disease not only of medical, but also economic and wider spoločenského standpoint. Diploma thesis linked hereditary breast malignancies I chose because since the beginning of the study of medicine is themed oncological diseases of women occupied . The elaboration of this thesis I considered it a great opportunity to find their way in a difficult and rapidly developing areas , such doubt carcinomas breast are . The incidence of breast cancer in the Czech Republic (the Czech Republic already ) the ascending tendency , mortality has stagnated in recent years . The lifetime risk of the disease on malignant neoplasm of breast cancer for a woman is around 10%. I am talking about is sporadically occurring carcinomas , which represent the majority of cases , but in the next lesser group ( 5-10 %) , which represent hereditary bonded malignancies , wherein the cause is mutation of the gene carrier of the mutation is at risk much higher risk celoživotným compared with the general population , up to 85%. Breast tumors also occur in men , does the general population only in very low numbers , but just in case linked hereditary...
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