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Use of Retomo software for computational modeling in biomechanics
Filková, Alena ; Lisický, Ondřej (referee) ; Marcián, Petr (advisor)
This bachelor thesis deals with the issue of musculoskeletal biomechanics. More precisely, of creating a geometry model based on CT data using the RETOMO program and then a computational model. The introductory part is devoted to a brief explanation of the concepts of computed tomography and finite element methods. The following chapter provides a search of programs used to create models of geometry from CT data in biomechanics. Furthermore, the work deals with the description of selected functionalities and user environment of the RETOMO program, with the greatest emphasis on the creation of a geometry model from CT data. During the implementation of the bachelor's thesis, two models of geometry were created in the analysed program, using different segmentation functions, which were then compared with each other and then compared with a model of geometry created in another program. The GOM Inspect program was used to compare the geometry deviations of individual models. Finally, computational models were created using the CATIA program and then deformation and stress analysis was performed using the ANSYS program. The results of individual solutions were analysed, compared and evaluated.
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Overview to arterial stents and possibilities of their computational modelling
Ondříšková, Tereza ; Lisický, Ondřej (referee) ; Turčanová, Michaela (advisor)
This bachelor thesis deals with arterial stents and possibilities of their computational modelling. The thesis contains a medical minimum, which is necessary to understand the principle of arterial stents. Furthermore, the thesis is focused on methods of a stent implantation, materials used for manufacturing and covering and the most used designs. There is a research study of analytical and numerical computational modelling of them with emphasis on the finite element method. In the last part of this thesis there was performed an analytical calculation of stress appeared in the carotid artery wall after stent implantation using a simplified model of stent-artery configuration. Then these stress functions were plotted and evaluated.
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Analysis of direction dispersion of collagen fibers in soft tissues
Sádovská, Terézia ; Lisický, Ondřej (referee) ; Turčanová, Michaela (advisor)
The bachelor thesis deals with the directional distribution of collagen fibres in soft tissues especially in arteries and tendons. The first part gives basic information about anatomy of human vascular system, particulary structure of the arteries. There are explained polarization microscopy principle of materials exhibiting birefringence. Further is described relation between direction of density and mechanical properties expresses as modulus in tensile. In the next section, we will be defined stress in arterial wall using linear stregth and stiffness. In the last part of thesis will be observed dispertion of collagen fibres in tendon. This dispertion is described by circular distribution Von Mises. At the end is evaluated how dispertion of collagen fibres effects mechanical properties of arteries.
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Effect of spine on stresses in abdominal aortic aneurysm
Lisický, Ondřej ; Horný,, Lukáš (referee) ; Polzer, Stanislav (advisor)
This thesis deals with stress strain analysis of an aortic abdominal aneurysm (AAA) and the influence of its contact with the spine on the extreme wall stress. The influence was tested on the idealized geometry, as well as on ten patient specific geometries obtained from computer tomography (CT-A) scans. Hyperelastic constitutive models were used for the AAA wall and intraluminal thrombus (ILT) tissue description. The prestress algorithm was used for reconstruction of the unloaded geometry to get more trustworthy results against the geometry from CT which was obtained under the blood pressure. Statistical analysis was used for the results evaluation. The maximal increase of peak wall stress was as high as 81 %.
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Impact of residual stresses and uncoiling of arterial specimen on its mechanical response
Sochor, Ondřej ; Lisický, Ondřej (referee) ; Burša, Jiří (advisor)
This thesis examines the impact of residual stresses in the carotid artery wall and the influence of specimen uncoiling on its mechanical response. The introductory part provides basic knowledge about the anatomy and the pathology of blood vessels, as well as overview of common methods used for testing artery samples. The main body of the thesis is divided into two sections. The first section focuses on the impact of specimen uncoiling on its mechanical response during the equibiaxial tensile test. It begins by describing the method used for sample testing and the method used for obtaining material constants from the mechanical response. These constants are then used as input for FEM simulation of the uncoiling and subsequent equibiaxial tensile test simulation on idealized model of geometry. The mechanical behaviour of the uncoiled model is compared to behaviour of the stress-free planar model to determine the influence of uncoiling. In the second section, the influence of residual stresses in the artery wall on its mechanical response is explored. This section includes a description of two methods used to show residual stress release, which are then used for specimen testing. The experiments are used to evaluate input parameters per layer for the model of geometry and subsequent FEM analysis. By comparing results from three levels of modeling, the impact of residual stresses on the artery’s mechanical response is determined.
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Stress-strain Analysis of Carotid Arteries with Atheroma
Lisický, Ondřej ; Návrat, Tomáš (referee) ; Vimmr, Jan (referee) ; Burša, Jiří (advisor)
Kardiovaskulární příhody byly a jsou rozšířenou příčinou úmrtí ve většině zemí. Ateroskleróza karotických tepen mnohdy vedoucí k mrtvici je jejich nedílnou součástí. Včasná a vhodně mířená diagnostika rizikových lézí může vést ke snížení kritických příhod, a tím potenciálně snížit počet úmrtí. Porušení nestabilního aterosklerotického plátu je ovlivněno působením sil od proudící krve. V biomechanice měkkých tkání je využíváno výpočtového modelování jakožto potenciálního ukazatele, díky němuž by bylo možné odhalit nestabilitu plátu u pacientů podstupujících pravidelná kontrolní měření. Mechanické veličiny bývají spojovány s klinicky dostupnými ukazateli jako jsou například podstatné rozměry léze nebo přítomnost rizikových komponent. Komplexita a malé rozměry tkáně ovšem stále omezují možnosti tvorby výpočtových modelů a existuje tedy spousta faktorů, které je před možnou implementací do klinických postupů potřeba řádně vyšetřit. Tato práce je členěna do kapitol shrnujících aktuální stav řešené problematiky. Kapitoly jsou doplněny o komentář autorova příspěvku k dané problematice a odkaz na originální práci. Studium problematiky naznačilo velké množství potenciálních směrů výzkumu, což by ovšem nebylo možné zahrnout do jediné práce. Řešená témata se dají rozdělit na: (i) ověření možnosti tvorby 3D výpočtového modelu ze snímků aterosklerotického plátu s následným rozšířením na výpočtovou studii zahrnující řadu faktorů pro ověření vlivu na napjatost, (ii) studium mechanických vlastností aterosklerotických plátů odebíraných z endarterektomie během celé doby řešení, (iii) možnosti analýzy deformačního pole u experimentů zahrnujících měkké tkáně a (iv) experimentální a výpočtovou studii zbytkové deformace, potažmo napětí v souvislosti s karotickými tepnami. Výsledky jednotlivých částí jednoznačně poukázaly na problémy spojené s výpočtovým modelováním jako například časté opomíjení přítomnosti komponent stěny tepny při modelování aterosklerotického plátu, nutnost správného pochopení mechanického chování, ale také na způsob vyhodnocení experimentů s vyšším počtem vzorků. V neposlední řadě bylo ukázáno, že zbytkové napětí nemusí být podstatným faktorem u aterosklerotických plátů karotických tepen.
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Overview to arterial stents and possibilities of their computational modelling
Ondříšková, Tereza ; Lisický, Ondřej (referee) ; Turčanová, Michaela (advisor)
This bachelor thesis deals with arterial stents and possibilities of their computational modelling. The thesis contains a medical minimum, which is necessary to understand the principle of arterial stents. Furthermore, the thesis is focused on methods of a stent implantation, materials used for manufacturing and covering and the most used designs. There is a research study of analytical and numerical computational modelling of them with emphasis on the finite element method. In the last part of this thesis there was performed an analytical calculation of stress appeared in the carotid artery wall after stent implantation using a simplified model of stent-artery configuration. Then these stress functions were plotted and evaluated.
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Use of Retomo software for computational modeling in biomechanics
Filková, Alena ; Lisický, Ondřej (referee) ; Marcián, Petr (advisor)
This bachelor thesis deals with the issue of musculoskeletal biomechanics. More precisely, of creating a geometry model based on CT data using the RETOMO program and then a computational model. The introductory part is devoted to a brief explanation of the concepts of computed tomography and finite element methods. The following chapter provides a search of programs used to create models of geometry from CT data in biomechanics. Furthermore, the work deals with the description of selected functionalities and user environment of the RETOMO program, with the greatest emphasis on the creation of a geometry model from CT data. During the implementation of the bachelor's thesis, two models of geometry were created in the analysed program, using different segmentation functions, which were then compared with each other and then compared with a model of geometry created in another program. The GOM Inspect program was used to compare the geometry deviations of individual models. Finally, computational models were created using the CATIA program and then deformation and stress analysis was performed using the ANSYS program. The results of individual solutions were analysed, compared and evaluated.
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Analysis of direction dispersion of collagen fibers in soft tissues
Sádovská, Terézia ; Lisický, Ondřej (referee) ; Turčanová, Michaela (advisor)
The bachelor thesis deals with the directional distribution of collagen fibres in soft tissues especially in arteries and tendons. The first part gives basic information about anatomy of human vascular system, particulary structure of the arteries. There are explained polarization microscopy principle of materials exhibiting birefringence. Further is described relation between direction of density and mechanical properties expresses as modulus in tensile. In the next section, we will be defined stress in arterial wall using linear stregth and stiffness. In the last part of thesis will be observed dispertion of collagen fibres in tendon. This dispertion is described by circular distribution Von Mises. At the end is evaluated how dispertion of collagen fibres effects mechanical properties of arteries.
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