National Repository of Grey Literature 3 records found  Search took 0.01 seconds. 
Investigating very high-frequency oscillations phenomena in human brain
Kolajová, Martina ; Cimbálník, Jan (referee) ; Klimeš, Petr (advisor)
Identifikace zóny vzniku záchvatu (SOZ) – oblasti mozku, kde začínají záchvaty – je klíčová pro úspěch chirurgické resekce epileptického ložiska. Význam vysokých vysokofrekvenčních oscilací (VHFO) spočívá v jejich roli jako více specifického biomarkeru této nemoci, přestože mechanismus jejich vzniku zůstává nejasný. Jednotlivé neurony nejsou fyziologicky schopné generovat oscilace v rozsahu VHFO. Je proto předpokládáno, že VHFO zaznamenané makroelektrodami mohou vznikat sumací aktivity různých neuronálních skupin, které pálí asynchronně. Tato diplomová práce se věnuje analýze jevů VHFO s důrazem na jejich vztah k epilepsii. Pomocí metod s využitím měření na mikroelektrodovém poli (MEA) jsou zkoumány mechanismy vzniku VHFO prostřednictvím analýzy dat v programovacím jazyce Python.
Quantification of Perfusion using MRI ASL Methods
Kolajová, Martina ; Mézl, Martin (referee) ; Jiřík, Radovan (advisor)
This bachelor thesis deals with quantification of perfusion using a contrast-free MRI technique called „Arterial Spin Labeling“ (ASL). Firstly, the physical principle of magnetic resonance imaging and the concept of perfusion will be described for better understanding of the subject. The next chapters will focus on the ASL method itself and perfusion quantification using mathematical models, namely T1 perfusion and Standard. The algorithm for preprocessing and analysis of selected datasets, designed in the thesis, is implemented using the program MATLAB. Program BASIL was used for further processing. The outputs in the form of perfusion and ATT maps and model fitting processes using various models from both programs are compared and evaluated.
Quantification of Perfusion using MRI ASL Methods
Kolajová, Martina ; Mézl, Martin (referee) ; Jiřík, Radovan (advisor)
This bachelor thesis deals with quantification of perfusion using a contrast-free MRI technique called „Arterial Spin Labeling“ (ASL). Firstly, the physical principle of magnetic resonance imaging and the concept of perfusion will be described for better understanding of the subject. The next chapters will focus on the ASL method itself and perfusion quantification using mathematical models, namely T1 perfusion and Standard. The algorithm for preprocessing and analysis of selected datasets, designed in the thesis, is implemented using the program MATLAB. Program BASIL was used for further processing. The outputs in the form of perfusion and ATT maps and model fitting processes using various models from both programs are compared and evaluated.

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