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Rozbor reprodukčních ukazatelů dosahovaných u prasniček a prasnic ve vybraném chovu
JEŘÁBKOVÁ, Adéla
The aim of this diploma thesis was to analyse the reproductive performance of sows at the particular farm during the time period 2018-2020. The highest number of piglets born alive was observed in 2018 (16.5 pcs; p < 0.05) with the highest rate seen among the sows that have had previously 3-5 litters (17.0; p < 0.05). The highest number of piglets born alive was observed at sows inseminated during the spring season. The average length of pregnancy of the sows during the monitored time period was 116 days. However, the highest number of piglets born alive was reached at sows with the pregnancy length between 110-115 days (16.6 pcs; p < 0.05). Most piglets born alive were born to gilts introduced to the breeding cycle at the age higher than 290 days (15.1 pcs). And lastly, most piglets born alive were born to the sows inseminated by the boar catalogued as #85 (17.1 pcs; p < 0.05). The number of stillborn piglets in 2018 was 2.3 pcs. The number increased to 3.1 pcs in 2019 and slightly decreased in 2020 to 3.0 pcs. The number of litters with 3 and more stillborn piglets was lowest (12%) during the 1st parity then it rapidly grew until it reached its peak during the observed period at the 8th parity (45%).
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The role of PGC1 in cardioprotective mechanisms
Jeřábková, Adéla ; Horníková, Daniela (advisor) ; Kolář, David (referee)
One of the leading causes of death worldwide is cardiovascular diseases. Researchers are, therefore, dealing with the mechanisms that induce a cardioprotection. Cardioprotection is a general pathophysiological term under which we understand myocytes protection against damage by ischemia and subsequent reperfusion impairment, inflammation, hypertension, and toxic and degenerative changes, including some types of apoptosis. One of the less common ways of cardioprotection is a cold adaptation. Adaptive thermogenesis is an important part of energy homeostasis and protection against obesity, metabolic disorder threatening heart. The PGC family of proteins plays a very important role in adaptive thermogenesis. This thesis summarizes the current state of literature in cold adaptation issues, especially the role of PGC1α and its effects at the cellular and tissue level. mRNA expression of PGC-1α is strongly induced in brown fat and skeletal muscles of mice exposed to cold. PGC-1α also increases the transcriptional activity of PPAR-γ and thyroid hormone receptor protein on UCP-1 (uncoupling protein). UCPs (uncoupling proteins) are small proteins localized to the inner side of the mitochondrial membrane to facilitate the transport of protons, which they release into concentration gradient without ATP...
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Faktory ovlivňující zabřezávání u prasnic
JEŘÁBKOVÁ, Adéla
The aim of the bachelor thesis was to evaluate the farrowing rate in gilts and sows in selected breeding group. The average farrowing rate of 80.9% was identical for sows and gilts. The highest farrowing rate of 84.0% was in year 2015. In year 2016, the farrowing rate decreased by 6.8% (77.2%) and in year 2017 there was an increase of 4.3% (81.5%). The differences were statistically significant. The highest farrowing rate (83.5%) was during the spring period. Winter and summer period showed similar farrowing rate (81.3% and 81.0%, respectively). The lowest farrowing rate (77.8%) was during the autumn period. The difference between the farrowing interval in spring and autumn was 5.7% (P < 0.05).
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The role of PGC1 in cardioprotective mechanisms
Jeřábková, Adéla ; Horníková, Daniela (advisor) ; Kolář, David (referee)
One of the leading causes of death worldwide is cardiovascular diseases. Researchers are, therefore, dealing with the mechanisms that induce a cardioprotection. Cardioprotection is a general pathophysiological term under which we understand myocytes protection against damage by ischemia and subsequent reperfusion impairment, inflammation, hypertension, and toxic and degenerative changes, including some types of apoptosis. One of the less common ways of cardioprotection is a cold adaptation. Adaptive thermogenesis is an important part of energy homeostasis and protection against obesity, metabolic disorder threatening heart. The PGC family of proteins plays a very important role in adaptive thermogenesis. This thesis summarizes the current state of literature in cold adaptation issues, especially the role of PGC1α and its effects at the cellular and tissue level. mRNA expression of PGC-1α is strongly induced in brown fat and skeletal muscles of mice exposed to cold. PGC-1α also increases the transcriptional activity of PPAR-γ and thyroid hormone receptor protein on UCP-1 (uncoupling protein). UCPs (uncoupling proteins) are small proteins localized to the inner side of the mitochondrial membrane to facilitate the transport of protons, which they release into concentration gradient without ATP...
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