|
|
Carbon - based electrodes: From detection of biologically significant compounds to application in neurodegenerative diseases
Jarošová, Romana ; Zima, Jiří (advisor) ; Vyskočil, Vlastimil (referee) ; Navrátil, Tomáš (referee)
CARBON BASED ELECTRODES: FROM DETECTION OF BIOLOGICALLY SIGNIFICANT COMPOUNDS TO APPLICATION IN NEURODEGENERATIVE DISEASES By Romana Jarošová Carbon is a truly remarkable element that is essential to life on Earth, and its unique properties have made it an indispensable component in an astonishingly diverse array of applications. Whether serving as a fuel source or as a key component in electronic devices, carbon's ability to exist in different forms, each with their distinct physical and chemical properties, contributes to its widespread and continued use. Electrode production is one of the areas where carbon found its significant use. This thesis represents a unique combination of fundamental and applied electrochemistry using carbon-based electrodes. It explores a wide range of topics, from evaluating electrode microstructure as a critical factor affecting its electroanalytical behavior, to the use of carbon- based electrodes in Alzheimer's disease (AD) research. The first part of this Thesis focuses on the electrochemical performance of carbon-based electrodes with distinct microstructures. Specifically, this section discusses two novel electrode materials: boron-doped diamond and nitrogen-incorporated tetrahedral amorphous carbon. The microstructure of each electrode was investigated, and the...
|
|
|
Determination of vanillin using carbon paste electrode
Jarošová, Romana ; Zima, Jiří (advisor) ; Daňhel, Aleš (referee)
Title: Determination of vanillin using carbon paste electrode. Abstract: The aim of this work is the determination of vanillin by flow injection analysis (FIA) with electrochemical detection using carbon paste electrode (CPE) and spectrophotometric detection. Optimal conditions for determination of vanillin by the FIA were found. Under optimal conditions calibration dependences were measured in the concentraction range from 1·10-4 mol·l-1 to 2·10-7 mol·l-1 . The calibration dependences were evaluated using linear regression method. Comparable results were achieved for the determination of vanillin by FIA with electrochemical detection using CPE and for the determination of vanillin by FIA with spectrophotometric detection. Limits of detection were identical 1.7·10-7 mol·l-1 . Key words: vanillin, carbon paste electrode, flow injection analysis, electrochemical detection, spectrophotometric detection
|
|
|
Electrochemical determination of carboxine using carbon paste electrode
Jarošová, Romana ; Dejmková, Hana (advisor) ; Vyskočil, Vlastimil (referee)
Pesticides are substances widely used for preventing damage by weeds, insects and fungi on plants, feedstuffs, foodstuffs, etc. Those compounds were often overused and this resulted in widespread contamination of the environment. Water ecosystem is the most endangered one - pesticides possess a huge risk for living organisms and primary sources of drinking water. Therefore, development of new analytical methods utilizable for reliable monitoring of these substances in environment is of necessity. Main objective of this diploma thesis was finding the optimal conditions for determination of carboxin using differential pulse voltammetry (DPV), high-performance liquid chromatography with spectrophotometric (HPLC-UV) and electrochemical (HPLC-ED) detection, latter using carbon paste electrode (CPE) as working electrode, reaching the lowest possible limits of detection (LD). Next objective was the application of the developed methods for the determination of carboxin in the sample matrix of river and drinking water. And since the recent trend in development of new analytical methods is their portability (usage in situ), application of miniaturized carbon paste electrode (mCPE) was investigated. Optimal conditions for voltammetric determination using CPE and mCPE were: mixture of Britton-Robinson buffer...
|
|
|
Electrochemical determination of carboxine using carbon paste electrode
Jarošová, Romana ; Dejmková, Hana (advisor) ; Vyskočil, Vlastimil (referee)
Pesticides are substances widely used for preventing damage by weeds, insects and fungi on plants, feedstuffs, foodstuffs, etc. Those compounds were often overused and this resulted in widespread contamination of the environment. Water ecosystem is the most endangered one - pesticides possess a huge risk for living organisms and primary sources of drinking water. Therefore, development of new analytical methods utilizable for reliable monitoring of these substances in environment is of necessity. Main objective of this diploma thesis was finding the optimal conditions for determination of carboxin using differential pulse voltammetry (DPV), high-performance liquid chromatography with spectrophotometric (HPLC-UV) and electrochemical (HPLC-ED) detection, latter using carbon paste electrode (CPE) as working electrode, reaching the lowest possible limits of detection (LD). Next objective was the application of the developed methods for the determination of carboxin in the sample matrix of river and drinking water. And since the recent trend in development of new analytical methods is their portability (usage in situ), application of miniaturized carbon paste electrode (mCPE) was investigated. Optimal conditions for voltammetric determination using CPE and mCPE were: mixture of Britton-Robinson buffer...
|
|
|
Determination of vanillin using carbon paste electrode
Jarošová, Romana ; Zima, Jiří (advisor) ; Daňhel, Aleš (referee)
Title: Determination of vanillin using carbon paste electrode. Abstract: The aim of this work is the determination of vanillin by flow injection analysis (FIA) with electrochemical detection using carbon paste electrode (CPE) and spectrophotometric detection. Optimal conditions for determination of vanillin by the FIA were found. Under optimal conditions calibration dependences were measured in the concentraction range from 1·10-4 mol·l-1 to 2·10-7 mol·l-1 . The calibration dependences were evaluated using linear regression method. Comparable results were achieved for the determination of vanillin by FIA with electrochemical detection using CPE and for the determination of vanillin by FIA with spectrophotometric detection. Limits of detection were identical 1.7·10-7 mol·l-1 . Key words: vanillin, carbon paste electrode, flow injection analysis, electrochemical detection, spectrophotometric detection
|
guest ::
RSS feed.