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Effect of biological treatment on functional ability and mobility of patients with ankylosing spondylitis
Hušková, Barbora ; Pavelka, Karel (advisor) ; Smolíková, Libuše (referee)
CHARLES UNIVERSITY IN PRAGUE 2ND FACULTY OF MEDICINE Department of Rehabilitation and Sport Medicine Barbora Hušková The influence of biological treatment on functional ability and mobility of patients with ankylosing spondylitis bachelor thesis Prague 2012 Abstract This thesis is primarily a literature search of knowledge about ankylosing spondylitis (AS), supplemented by two case studies of specific patients. The theoretic part describes the characteristics of AS as the main representative of spondylarthritides, including its diagnosis and testing methods. It also contains an overview of current approaches and strategies of a treatment. It focuses on biological treatment with TNF-α blockers. The practical part of the thesis illustrates the findings on the example of a patient with AS treated with biological therapy. It evaluates the subjective feelings in response to treatment and compares the results of treatment with standard therapy (i.e., without biological treatment) on another patient under otherwise similar conditions.
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Effect of biological treatment on functional ability and mobility of patients with ankylosing spondylitis
Hušková, Barbora ; Pavelka, Karel (advisor) ; Smolíková, Libuše (referee)
CHARLES UNIVERSITY IN PRAGUE 2ND FACULTY OF MEDICINE Department of Rehabilitation and Sport Medicine Barbora Hušková The influence of biological treatment on functional ability and mobility of patients with ankylosing spondylitis bachelor thesis Prague 2012 Abstract This thesis is primarily a literature search of knowledge about ankylosing spondylitis (AS), supplemented by two case studies of specific patients. The theoretic part describes the characteristics of AS as the main representative of spondylarthritides, including its diagnosis and testing methods. It also contains an overview of current approaches and strategies of a treatment. It focuses on biological treatment with TNF-α blockers. The practical part of the thesis illustrates the findings on the example of a patient with AS treated with biological therapy. It evaluates the subjective feelings in response to treatment and compares the results of treatment with standard therapy (i.e., without biological treatment) on another patient under otherwise similar conditions.
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Rural renewal - a small village example
Hušková, Barbora ; Majerová, Věra (advisor) ; Petra, Petra (referee)
This thesis, created under the topic of rural renewal, illustrates the rural area and its renewal topic on the example of a small village, specifically East Bohemian village Kosice. To do so it firstly defines a theoretical platform consisting of core concepts in rural areas such as country, village, municipality and influencing entities. The second part of this thesis contains theoretical studies focusing on rural development and renewal with the definition of development support instruments, levels and entities; it also describes potentials and summarizes factors and trends affecting rural life, including migration trends.
The first practical part studies and analyzes Kosice, its development over time and current situation which enables inclusion of the village among the rural ones and determination of the research basis. The actual research is based on acquired theoretical and practical knowledge. To consider local specifics a qualitative research consisting of an interview with a mayor is carried out, followed by a quantitative research through questionnaire survey to gain the residents´ perspective on the current development and the possible future development of the village. The results are processed using statistical methods and used to propose recommendations to the village for its future activities according to the obtained opinion of its population.
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