|
|
Treatment of diabetes mellitus
Hrouzková, Šárka ; Tilšer, Ivan (advisor) ; Hrdina, Radomír (referee)
DM is metabolic disorder characterized with hyperglycaemia at absolute shortage of endogenous insulin (DM1T), or at its relative shortage (DM2T). DM1T is a symptom of B-cell destruction in islets of pancreas Langerhans that occurs mostly on autoimmune basis. Lack of insulin results in disorder of glucose use and in increased catabolism of fat and proteins. The result of this disorder is hyperglycaemia, glycosuria, polyuria, thirst, eventually ketoacidotic coma. DM2T which prevalence is continuously increasing represents significant medical, social and economic problem. DM2T develops due to insulin resistance and later due to insufficient insulin secretion after each meal. Insulin resistance mostly develops in connection with obesity. In the course of disorder the defect of insulin secretion gradually worsens and micro and macro vascular complications develops that are the most frequent cause of death of patient suffering from the disorder. Diabetes treatment is of complicated and complex nature that has to be based on simultaneous intensive therapy, prevention, collaboration with patient, education, individual adjustment of treatment and therapeutic goals. The Czech Republic belongs to a few countries where diabetology as an independent branch of medicine exists. The goal of treatment is to ensure...
|
|
|
Treatment of diabetes mellitus
Hrouzková, Šárka ; Tilšer, Ivan (advisor) ; Hrdina, Radomír (referee)
DM is metabolic disorder characterized with hyperglycaemia at absolute shortage of endogenous insulin (DM1T), or at its relative shortage (DM2T). DM1T is a symptom of B-cell destruction in islets of pancreas Langerhans that occurs mostly on autoimmune basis. Lack of insulin results in disorder of glucose use and in increased catabolism of fat and proteins. The result of this disorder is hyperglycaemia, glycosuria, polyuria, thirst, eventually ketoacidotic coma. DM2T which prevalence is continuously increasing represents significant medical, social and economic problem. DM2T develops due to insulin resistance and later due to insufficient insulin secretion after each meal. Insulin resistance mostly develops in connection with obesity. In the course of disorder the defect of insulin secretion gradually worsens and micro and macro vascular complications develops that are the most frequent cause of death of patient suffering from the disorder. Diabetes treatment is of complicated and complex nature that has to be based on simultaneous intensive therapy, prevention, collaboration with patient, education, individual adjustment of treatment and therapeutic goals. The Czech Republic belongs to a few countries where diabetology as an independent branch of medicine exists. The goal of treatment is to ensure...
|
guest ::
