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Hot forging of projectile
Frydrych, Jan ; Císařová, Michaela (referee) ; Lidmila, Zdeněk (advisor)
The project elaborated design of technology production of artillery shell – thick walled component from plain steel 11 503. Based on the research of press forging and calculations, it was proposed to forge with production line which contains two forging presses. These allow us to use special way of forging. The forged piece is broached through several pulleys and its diameter is slowly getting smaller and required form is made. Forging tools and forging dies are made from steel 19 552
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Konstrukční návrh bezpilotního letadla pro aplikaci v zemědělství
Frydrych, Jan
The diploma thesis deals with structural design of unmanned aircraft for application in agriculture. Thesis describes precision agriculture, agricultural machines, unmanned aircrafts, and technology of 3D printing. An analysis of these topics is performed, and it is also mentioned the legislation for using unmanned drone in the Czech Republic. In the second part the diploma thesis is focusing on structural design of unmanned aircraft and its individual parts. The structural design is extended by a draft of docking station which also works for charging the aircraft. The production technology was chosen 3D printing using PET-G material. In the end of the thesis, the process of 3D printing and mechanical testing of ASA, PET-G and rPET-G materials is described.
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Synthetic routes to 2-phenylbenzothiazoles with potential application in cancer therapy and PET imaging
Frydrych, Jan ; Opletalová, Veronika (advisor) ; Zimčík, Petr (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Drug Control Candidate: Jan Frydrych Supervisors: Assoc. Prof. RNDr. Veronika Opletalová, Ph.D. Dr. Andrew Westwell Ph.D. Title of diploma thesis: Synthetic routes to 2-phenylbenzothiazoles with potential application in cancer therapy and PET imaging There are three main tasks reported in this thesis. The first is the report of an improved procedure for synthesis of biologically relevant 2-phenylbenzothiazoles with various substituents on phenyl ring. Reported 2-phenylbenzothiazoles were synthesised by heating equimolar amounts of 2-aminothiophenol disulfides with appropriate benzaldehydes with p-toluenesulfonic acid in the presence of polymer-bound triphenylphosphine using mixture of toluene and DMF as a solvent. Main features of reported method include simple product isolation (removal polymer-bound by-product by filtration through Celite® layer), avoidance of column chromatography, rapid synthesis and good yields of correspondent benzothiazole. The second goal of this thesis is the solution phase synthesis of 2-phenylbenzothiazoles bearing different substituents on both the benzothiazole and phenyl ring. Attempts were made to synthesise different 2-phenylbenzothiazoles by heating...
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Hot forging of projectile
Frydrych, Jan ; Císařová, Michaela (referee) ; Lidmila, Zdeněk (advisor)
The project elaborated design of technology production of artillery shell – thick walled component from plain steel 11 503. Based on the research of press forging and calculations, it was proposed to forge with production line which contains two forging presses. These allow us to use special way of forging. The forged piece is broached through several pulleys and its diameter is slowly getting smaller and required form is made. Forging tools and forging dies are made from steel 19 552
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Synthetic routes to 2-phenylbenzothiazoles with potential application in cancer therapy and PET imaging
Frydrych, Jan ; Opletalová, Veronika (advisor) ; Zimčík, Petr (referee)
Charles University in Prague Faculty of Pharmacy in Hradec Králové Department of Pharmaceutical Chemistry and Drug Control Candidate: Jan Frydrych Supervisors: Assoc. Prof. RNDr. Veronika Opletalová, Ph.D. Dr. Andrew Westwell Ph.D. Title of diploma thesis: Synthetic routes to 2-phenylbenzothiazoles with potential application in cancer therapy and PET imaging There are three main tasks reported in this thesis. The first is the report of an improved procedure for synthesis of biologically relevant 2-phenylbenzothiazoles with various substituents on phenyl ring. Reported 2-phenylbenzothiazoles were synthesised by heating equimolar amounts of 2-aminothiophenol disulfides with appropriate benzaldehydes with p-toluenesulfonic acid in the presence of polymer-bound triphenylphosphine using mixture of toluene and DMF as a solvent. Main features of reported method include simple product isolation (removal polymer-bound by-product by filtration through Celite® layer), avoidance of column chromatography, rapid synthesis and good yields of correspondent benzothiazole. The second goal of this thesis is the solution phase synthesis of 2-phenylbenzothiazoles bearing different substituents on both the benzothiazole and phenyl ring. Attempts were made to synthesise different 2-phenylbenzothiazoles by heating...
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Motivating potential of the sojourn services of the social prevention for accommodation of "rough sleepers" in the Czech Republic
Frydrych, Jan ; Čabanová, Bohumila (advisor) ; Orságová, Petra (referee)
My Master thesis called Motivating potential of the sojourn services of the social prevention for accommodation of "rough sleepers" in the Czech Republic is concerned with the opportunities to increase the attractiveness of already mentioned services for the target group via the change of accommodation conditions or via the creation of new services to lower the number of homeless people. The basic research problem of my thesis consists in hypothesis verification of need for "low-liminal" sojourn service stimulating the willingness for social integration of dependent members of the target group in particular. The starting point for my work is the right to help in accommodation and motivation for social integration by means of life quality enhancement, namely by providing the concern in helpful social sojourn services. In the theoretical part, the analysis of strategy and basic legal regulation reducing the issue of homelessness is worked out, chosen services of social prevention, apt for inclusion of the target group in our country and in Great Britain and their motivating potential, are reviewed; furthermore the special Danish and Slovak innovative solutions are mentioned. Practical part represents three tapered established variants of the possible innovative solutions of the problem - "shelter...
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