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Evolutionary hypotheses of obesity origin
Dundr, Matěj ; Hora, Martin (advisor) ; Vážná, Anna (referee)
Obesity is a major social, ecological, economic and health problem of today's civilization. Humans evolved to adapt to a different environment than the one they live in today, had more exercise and consumed natural food sources. The imbalance in energy intake and expenditure that we observe in today's human populations is the most likely cause of obesity. However, this work will deal with a less discussed view of the origin of obesity, namely the possible explanation of the origin of obesity with evolutionary hypotheses. The work will also try to evaluate and discuss, based on a comparison of the available literature, whether these hypotheses could really clarify the origin of obesity at the global level. In the beginning of the thesis, we present the problem of obesity, its prevalence in the population and comorbidities associated with obesity. The next section describes the diagnosis of obesity, followed by a section on the history of obesity. The main part is devoted to the evolutionary hypotheses of obesity, namely the adaptation to frugality hypothesis, the genetic drift hypothesis and then other ecological- behavioral hypotheses and their evaluation. In conclusion, the work summarizes that the described hypotheses could be useful for clarifying the difference in obesity prevalence between...

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