|
|
Urban gardening as a social phenomenon (case study Prazelenina)
Hofman, Jiří ; Novák, Arnošt (advisor) ; Dostalík, Jan (referee)
New phenomenon of urban gardening is taking place also in the Czech republic. Even it's quite common in the USA, Great Britain, Germany, Scandinavia or Spain, that urban gardens have a long history and sometimes also a political intentions, in the Czech republic it is still a new phenomenon. In 2012a new urban gardening project called Prazelenina started in Prague 7 Holešovice. I decided to focus on it using qualitative research methods and find out how is Prazelenina going on. I will also deal with possibilities of a resistance to pressures of individualization and commodification in life of Prazelenina.
|
|
|
Determination of tumor mRNA in colorectal cancer as screening and forecasting methods
Rupert, Karel ; Holubec, Luboš (advisor) ; Hoch, Jiří (referee) ; Pešková, Marie (referee) ; Dostalík, Jan (referee)
The level of MMP-7, TIMP-1 and MMP-2 mRNA expression was significantly higher in the tumour tissue of colorectal carcinoma than in normal colorectal tissue. It could be possible to inhibit matrix metalloproteinases activity using appropriate antibodies, which could have therapeutic effect on tumour tissue and its vicinity. Some of the preparations are being tested (Bay 12-9566 /Bayer/, BB94 /British Biotechnology/). We have not proved correlation between expression of these genes and disease stage and diagnosis. We have succeeded to prove that if the surgical principles for colon resection performed due to colorectal carcinoma are observed, the resection line does not show any signs of the presence of tumour cells - mRNA for CEA is not present. The level of mRNA for TIMP-1 is present in the resection line at lower levels than in tumour tissue, and this is due to the role that TIMP- 1 plays in the colon. Its level increases not only in all tumour diseases, but also in inflammatory diseases of the colon. The question whether the expression of mRNA for TIMP-1 is also increased outside the resection line and therefore it is a reaction of the colon as an organ will be subject to further research, as will be a potential comparison with samples of colon unaffected by tumour or inflammation. Although the...
|
|
|
Urban gardening as a social phenomenon (case study Prazelenina)
Hofman, Jiří ; Novák, Arnošt (advisor) ; Dostalík, Jan (referee)
New phenomenon of urban gardening is taking place also in the Czech republic. Even it's quite common in the USA, Great Britain, Germany, Scandinavia or Spain, that urban gardens have a long history and sometimes also a political intentions, in the Czech republic it is still a new phenomenon. In 2012a new urban gardening project called Prazelenina started in Prague 7 Holešovice. I decided to focus on it using qualitative research methods and find out how is Prazelenina going on. I will also deal with possibilities of a resistance to pressures of individualization and commodification in life of Prazelenina.
|
|
|
Determination of tumor mRNA in colorectal cancer as screening and forecasting methods
Rupert, Karel ; Holubec, Luboš (advisor) ; Hoch, Jiří (referee) ; Pešková, Marie (referee) ; Dostalík, Jan (referee)
The level of MMP-7, TIMP-1 and MMP-2 mRNA expression was significantly higher in the tumour tissue of colorectal carcinoma than in normal colorectal tissue. It could be possible to inhibit matrix metalloproteinases activity using appropriate antibodies, which could have therapeutic effect on tumour tissue and its vicinity. Some of the preparations are being tested (Bay 12-9566 /Bayer/, BB94 /British Biotechnology/). We have not proved correlation between expression of these genes and disease stage and diagnosis. We have succeeded to prove that if the surgical principles for colon resection performed due to colorectal carcinoma are observed, the resection line does not show any signs of the presence of tumour cells - mRNA for CEA is not present. The level of mRNA for TIMP-1 is present in the resection line at lower levels than in tumour tissue, and this is due to the role that TIMP- 1 plays in the colon. Its level increases not only in all tumour diseases, but also in inflammatory diseases of the colon. The question whether the expression of mRNA for TIMP-1 is also increased outside the resection line and therefore it is a reaction of the colon as an organ will be subject to further research, as will be a potential comparison with samples of colon unaffected by tumour or inflammation. Although the...
|
|
| |
guest ::
RSS feed.