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Interstitial Brachytherapy of the Breast and Penis
Pohanková, Denisa ; Petera, Jiří (advisor) ; Doležel, Martin (referee) ; Cvek, Jakub (referee)
Interstitial brachytherapy of the breast and penis Summary Aims: Interstitial brachytherapy (BT) is a therapeutic method with a proven history used in treatment of various cancers. In our work we focused on accelerated partial breast irradiation with multicatheter interstitial brachytherapy (MIB APBI) of early breast cancer due to the high incidence of this disease and on BT of early penile cancer as an alternative to primary surgical treatment. Methods and materials: 1) High dose rate brachytherapy (HDR BT) for MIB APBI of early breast cancer has been used at the Department of Oncology and Radiotherapy, University Hospital and Medical Faculty, Hradec Králové since 2012. Brachytherapy catheters are inserted perioperatively in the time of tumorectomy and sentinel node biopsy. APBI starts on day 6 after surgery. The prescribed dose was 34 Gy in 10 fractions applied twice a day. We evaluated 125 patients with minimum follow up of 2 years. 2) Twenty-eight patients with early penile cancer underwent HDR brachytherapy between 2002-2020. The prescribed dose was 18x 3 Gy applied twice a day. Results: 1) One hundred twenty-five patients were indicated for APBI, 12 patients of these did not receive this treatment (9.6 %) due to adverse prognostic factors in the final histology. In these patients the inserted...
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Technické vybavení na interakci elektromagnetických polí a biologické systémy
Vrba, J. ; Vannucci, Luca ; Peschke, P. ; Vožeh, F. ; Vojtíšek, M. ; Kubeš, J. ; Herza, J. ; Cvek, J. ; Dřížďal, T. ; Zajíček, R.
Research experiments with influence of electro-magnetic (EM) fields on biologic systems request special technical devices. We describe our own a pproach to technical equipment for research projects being solved here in Czech Republic in cooperation with experts from Italy and Germany
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